Publications by authors named "Xinai Ma"
Article Synopsis
- * Silibinin (Sil) has potential as a treatment for NAFLD, but its effectiveness is limited due to poor absorption and bioavailability, prompting researchers to create a Sil-loaded liposome (Sil-Lip) to enhance its therapeutic effects.
- * The study found that Sil-Lip improved gastrointestinal stability and absorption, leading to better outcomes in lipid metabolism, insulin resistance, and inflammation in NAFLD models compared to Sil alone, and operated through specific signaling pathways and gut microbiota modulation.
Idiopathic pulmonary fibrosis (IPF) is a kind of life-threatening interstitial lung disease characterized by progressive dyspnea with accurate pathogenesis unknown. At present, heat shock protein inhibitors are gradually used to treat IPF. Silybin, a heat shock protein C-terminal inhibitor, has high safety and good application prospects.
View Article and Find Full Text PDFThe present study explored the correlation between the hydrodynamic size(i.e., hydrated particle size) and the surface component distribution of spray-dried powder based on the binary system model of berberine hydrochloride and dextran.
View Article and Find Full Text PDFCholesterol Microdomain Enhances the Biofilm Eradication of Antibiotic Liposomes.
Adv Healthc Mater
April 2022
Resistance and tolerance of biofilms to antibiotics is the greatest challenge in the treatment of bacterial infections. Therefore, developing an effective strategy against biofilms is a top priority. Liposomes are widely used as antibiotic drug carriers; however, common liposomes lack affinity for biofilms.
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