Background: Laparoscopic gastrectomy lacks hand-direct tactile sense and has a limited surgical field compared to laparotomy. Apart from textbook classification, there are anatomical variations in the gastric arteries. Laparoscopic gastrectomy presents technical difficulties and necessitates a more comprehensive comprehension of regional anatomy than open surgical procedures.
View Article and Find Full Text PDFBackground: Sarcomatoid carcinoma of the small bowel is an exceedingly rare gastrointestinal tumor characterized by a biphasic cellular pattern of epithelioid and mesenchymal-like cells. Due to its rarity and non-specific clinical presentation, it is frequently misdiagnosed, and there is a lack of standardized management guidelines. We report a case of multiple sarcomatoid carcinoma of the small intestine, presenting initially with gastrointestinal perforation.
View Article and Find Full Text PDFThe Advanced Lung Cancer Inflammation Index (ALI) represents both the inflammatory and nutritional status of the host, but its link with mortality in asthma patients is uncertain. The purpose of this study was to look at the relationship between ALI levels and all-cause and respiratory disease mortality in asthmatic patients. We conducted our research using cohort data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018.
View Article and Find Full Text PDFThe 2030 Agenda for Sustainable Development issued by the United Nations is an important foundation for countries to achieve common economic, social and environmental development. Important progress has been made in the evaluation of the Sustainable Development Goals (SDGs) in Hainan Island; nevertheless, there is still a lack of understanding around the trade-offs and synergies between the SDGs. Studying the trade-offs and synergies between Hainan Island's sustainable development goals is of great significance for the coordinated development of these goals and the promotion of the construction of free trade ports.
View Article and Find Full Text PDFRecent studies have established an association between variants and Perrault syndrome. In this case report, we present a female patient with Perrault syndrome and cardiomyopathy, resulting from variants in and , respectively.
View Article and Find Full Text PDFThe subsidence caused by coal mining could cause the destruction of roads and houses, and even the failure of infrastructures. Understanding of the mechanism of coal mining subsidence may provide early protecting to infrastructures on coming failure, but dynamic analysis of subsidence due to coal mining is currently needed. In this study we apply particle image velocimetry (PIV) method to reveal strata movement and subsidence according to the prototype and indoor physical model similarity experiment of Henan.
View Article and Find Full Text PDFBackground: The HALP score, comprising hemoglobin, albumin, lymphocyte, and platelet levels, serves as an indicator of both nutritional and inflammatory status. However, its correlation with all-cause and cause-specific mortality among cancer survivors remains unclear. Therefore, this study aims to investigate the relationship between HALP scores and mortality outcomes in this population.
View Article and Find Full Text PDFBackground: Exosomes released by cardiomyocytes are essential mediators of intercellular communications within the heart, and various exosomal proteins and miRNAs are associated with cardiovascular diseases. However, whether the endosomal sorting complex required for transport (ESCRT) and its key component Alix is required for exosome biogenesis within cardiomyocyte remains poorly understood.
Methods: Super-resolution imaging was performed to investigate the subcellular location of Alix and multivesicular body (MVB) in primary cardiomyocytes.
Background: Cardiac transverse tubules (T-tubules) are anchored to sarcomeric Z-discs by costameres to establish a regular spaced pattern. One of the major components of costameres is the dystrophin-glycoprotein complex (DGC). Nevertheless, how the assembly of the DGC coordinates with the formation and maintenance of T-tubules under physiological and pathological conditions remains unclear.
View Article and Find Full Text PDFMicromachines (Basel)
November 2023
Micro-Electro-Mechanical System (MEMS) inertial sensors, characterized by their small size, low cost, and low power consumption, are commonly used in foot-mounted wearable pedestrian autonomous positioning systems. However, they also have drawbacks such as heading drift and poor repeatability. To address these issues, this paper proposes an improved pedestrian autonomous 3D positioning algorithm based on dual-foot motion characteristic constraints.
View Article and Find Full Text PDFObjective: The Omicron BA.5.2 variant of SARS-CoV-2 has undergone several evolutionary adaptations, leading to multiple subvariants.
View Article and Find Full Text PDFYeast flocculation and viability are critical factors in beer production. Adequate flocculation of yeast at the end of fermentation helps to reduce off-flavors and cell separation, while high viability is beneficial for yeast reuse. In this study, we used comparative genomics to analyze the genome information on W01, and its spontaneous mutant W02 with appropriate weakened flocculation ability (better off-flavor reduction performance) and unwanted decreased viability, to investigate the effect of different gene expressions on yeast flocculation or/and viability.
View Article and Find Full Text PDFThe ability of cancer stem cells (CSCs) to self-renew, differentiate, and generate new tumors is a significant contributor to drug resistance, relapse, and metastasis. Therefore, the targeting of CSCs for treatment is particularly important. Recent studies have demonstrated that CSCs are more susceptible to ferroptosis than non-CSCs, indicating that this could be an effective strategy for treating tumors.
View Article and Find Full Text PDFSplenic hilar vascular injury may occur during laparoscopic radical total gastrectomy for splenic hilar lymph node dissection and often causes massive hemorrhage, requiring conversion to laparotomy and splenectomy. Surgeons treating splenic hilar vascular injuries need a way to stop bleeding promptly and accurately. Herein, we report a case of splenic hilar vascular injury during laparoscopic total gastrectomy in which we successfully managed to stop the bleeding and preserve the spleen.
View Article and Find Full Text PDFMetasurfaces consisting of planar subwavelength structures with minimal thickness are appealing to emerging technologies such as integrated optics and photonic chips for their small footprint and compatibility with sophisticated planar nanofabrication techniques. However, reduced dimensionality due to the 2D nature of a metasurface poses challenges to the adaptation of a few useful methods that have found great success with conventional optics in 3D space. For instance, Bragg diffraction is the foundation of the well-established technique of phase-coded multiplexing in volume holography.
View Article and Find Full Text PDFThis paper examines seafarers' experience of fatigue during and after the pandemic. A multi-phase mixed methods research design was used, including two quantitative surveys (N and N) and 36 in-depth interviews. Applying propensity score matching the two samples to approximate the conditions of a randomized controlled experiment, the study shows that surprisingly seafarers reported higher levels of fatigue after the pandemic.
View Article and Find Full Text PDFComput Struct Biotechnol J
February 2023
The endoplasmic reticulum (ER) and microtubule (MT) network form extensive contact with each other and their interconnection plays a pivotal role in ER maintenance and distribution as well as MT stability. The ER participates in a variety of biological processes including protein folding and processing, lipid biosynthesis, and Ca storage. MTs specifically regulate cellular architecture, provide routes for transport of molecules or organelles, and mediate signaling events.
View Article and Find Full Text PDFZ Angew Math Phys
February 2023
This paper studies the propagation thresholds in a diffusive epidemic model with latency and vaccination. When the initial condition satisfies proper exponential decaying behavior, we present the spatial expansion feature of the infected. Different leftward and rightward spreading speeds are obtained with respect to different decaying initial values.
View Article and Find Full Text PDFRationale: Lung cancer (LC) is a malignant tumor with the highest morbidity and mortality in the world. The most common metastatic sites of LC are the brain (47%), bone (36%), liver (22%), adrenal glands (15%), thoracic cavity (11%) and distant lymph nodes (10%). Peritoneal carcinomatosis (PC) is a rare clinical event in LC patients.
View Article and Find Full Text PDFIn this paper, Nostoc commune crude polysaccharide was extracted by heating and Ultrasonic-assisted methods separately, homogeneous polysaccharide HNCP3 and UNCP4 were obtained after purified by DEAE-52 cellulose column chromatography and Sephacryl G-100 gel column chromatography. The structures of HNCP3 and UNCP4 were characterized by molecular weight determination, infrared spectroscopy, DSC detection, sodium periodate oxidation, smith degradation reaction and methylation analysis. The conformation of the solution was studied by SEM and AFM.
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