Publications by authors named "Xin-wei Chen"

All-solid-state potassium metal batteries have caught increasing interest owing to their abundance, cost-effectiveness, and high energy/power density. However, their development is generally constrained by the lack of suitable solid-state electrolytes. Herein, we report a new complex KCBH ⋅ 2CHN, synthesized by grinding and heating the mixture of potassium decahydrido-monocarba-closo-decaborate (KCBH) and imidazole (CHN) under mild conditions, to achieve the K-ion superionic solid-state electrolyte.

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Solid-state sodium metal batteries have been extensively investigated because of their potential to improve safety, cost-effectiveness, and energy density. The development of such batteries urgently required a solid-state electrolyte with fast Na-ion conduction and favorable interfacial compatibility. Herein, the progress on developing the NaBH solid-state electrolytes is reported, which show a liquid-like ionic conductivity of 0.

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Two-dimensional kagome metals possess rich band structure characteristics, including Dirac points, flat bands, and van Hove singularities, because of their special geometric structures. Furthermore, kagome metals AVSb (A = K, Rb, and Cs) have garnered significant attention due to their nontrivial topological electronic structures. In this study, we theoretically demonstrate that the KVSb (001) surface is conducive to CO and CO reduction.

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Sodium ion batteries possess several advantages for large-scale energy storage, such as low cost and enhanced safety. However, graphite or other anode materials are not satisfactory because the large radius of Na hinders their embedding and removal in the charge and discharge processes. Recently, a biphenylene network (BPN), a two-dimensional (2D) carbon allotrope, has been synthesized.

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A 7-year-old intact female domestic medium hair cat was examined at a veterinary clinic for a scabbed nodule over the right shoulder. Multiple nodules recurred at the same site after the first surgical excision, and a second surgical excision was performed. Histopathology demonstrated high-mitotic-rate neoplastic cells and therefore a histiocytic proliferative disease was initially suspected.

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As a new type of topological magnet, TbMnSn has a planar Mn kagome lattice with out-of-plane magnetic moments. Previous studies have found spin-polarized Chern gapped Dirac fermions in TbMnSn, which are advantageous to topological catalysis. In this study, we theoretically demonstrate that the TbMnSn (001) surface is favorable for CO reduction.

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Article Synopsis
  • * Using various bioinformatics tools, the study found elevated levels of SLC30A1, SLC30A7, and SLC30A10 in cervical cancer tissues compared to normal ones, while SLC30A2 and SLC30A8 levels decreased.
  • * High expression of certain SLC30 genes is linked to worse survival outcomes for cervical cancer patients and could offer insights for new diagnostic and therapeutic strategies.
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As promising catalytic systems, single-atom catalysts (SACs) demonstrate improved catalytic performance for electrochemical reactions. However, the pinning of metal atoms on surfaces usually depends on the adsorption on defects. In this study, defect-free functionalization by attaching IrX (X = F or Cl) complexes on the MoS monolayer is theoretically demonstrated.

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Purpose: To compare the mechanical properties of 3D-printed titanium meshes and pre-shaped titanium meshes, and to evaluate the effects of 3D-printed titanium meshes on cell proliferation and differentiation.

Methods: 3D- printed titanium meshes were produced and prepared with laser printing machine. The mechanical properties were analyzed by static tension and compression load test.

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This study aimed at clarifying the mechanism and role of survivin in hypoxia-induced multidrug resistance (MDR) of laryngeal carcinoma cells. Human laryngeal cancer cells were incubated under hypoxia or normoxia. The expression of was silenced by performing RNA interference.

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Lactoferrin (LF) is an iron-binding glycoprotein that plays an important role in promoting bone formation and inhibiting bone resorption; however, its effects on senile osteoporosis remain unknown. This study aimed to investigate the effects and mechanism of LF intervention using a senile osteoporosis model (SAMP6 mice) and senescent osteoblasts. Micro-CT and hematoxylin and eosin staining demonstrated that the intragastric administration (2 g/kg/day) of LF could improve the bone mass and microstructure of SAMP6 mice.

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Article Synopsis
  • Ternary bulk heterojunction (BHJ) organic solar cells (OSCs) utilize multiple donor and acceptor materials to enhance light absorption and improve performance.
  • The study introduced coumarin7 (C7) as a new electron-donor component in combination with traditional materials, resulting in a power conversion efficiency (PCE) of 10.28%, which is a significant 35% increase compared to standard OSCs.
  • The improved efficiency is attributed to better charge transport and reduced recombination due to a compatible nanofiber morphology, suggesting that structurally diverse materials like coumarin derivatives can lead to high-performing ternary solar cells with further optimization.
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Objective: To investigate the possible mechanisms of oxymatrine's role in anti laryngeal squamous cell carcinoma.

Methods: We examined the effects of oxymatrine on the proliferation, cell cycle phase distribution, apoptosis, and the protein and mRNA expression levels of HPV16E7 gene in laryngeal carcinoma Hep-2 cells in vitro. The HPV16E7 siRNA inhibition was also done to confirm the effect of downregulating HPV16E7 on the proliferation in Hep-2 cells.

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Objectives: To investigate whether hypoxia has an effect on regulation of multidrug resistance (MDR) to chemotherapeutic drugs in laryngeal carcinoma cells and explore the role of hypoxia-inducible factor-1α (HIF- 1α).

Methods: Laryngeal cancer cells were cultured under normoxic and hypoxic conditions. The sensitivity of the cells to multiple drugs and levels of apoptosis induced by paclitaxel were determined by MTT assay and annexin-V/propidium iodide staining analysis, respectively.

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The present study aimed to evaluate the expression of hypoxia-inducible factor-1α (HIF-1α) and MDR1/P-glycoprotein (P-gp) in human laryngeal squamous cell carcinoma (LSCC) tissues, and also to investigate the regulation of gene expression by HIF-1α in Hep-2 cells under hypoxic conditions. The expression of HIF-1α and MDR1/P-gp in human LSCC tissues was examined using immunohistochemistry. The and gene expression in the Hep-2 cells was detected using real-time quantitative reverse transcription (QRT)-PCR and western blot analysis under normoxic and hypoxic conditions.

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Article Synopsis
  • Paclitaxel is an important chemotherapy drug used for advanced laryngeal cancer, but 20-40% of patients don't respond, prompting the search for biomarkers predicting sensitivity to the drug.
  • In a study using the Hep2 laryngeal cancer cell line, treatment with a low dose of paclitaxel revealed significant changes in the expression of eight genes and 49 microRNAs (miRs) after 24 hours.
  • The findings suggest that certain up-regulated and down-regulated genes, along with specific miRs, could serve as potential biomarkers for predicting how well patients will respond to paclitaxel treatment.
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In order to understand the secondary productivity of macrobenthos in different botanic habitats in intertidal zone in Gaoqiao of Zhanjiang, the Brey's empirical formula was applied to calculate the secondary productivity based on the investigations in the habitats of Sonneratia apetala, Aegiceras corniculatum, Sporobolus virginicus, and Bruguiera conjugate in four seasons, 2010. The secondary productivity of the macrobenthos in the habitats in four seasons was averagely 11.77 g AFDM x m(-2) x a(-1), being the highest in S.

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In order to understand the community structure of polychaete in different botanic habitats in Zhangjiang River Estuary, an investigation was conducted in the habitats of Kandelia candel, Aegiceras corniculatum, Spartina alterniflora, and Avicennia marina in four seasons, 2010. A total of 15 polychaete species were recorded, and 6 species including Eteone delta, Namalycastis abiuma, Paraleonnates uschakovi, Polydora ciliata, Capitella capitata, and Mediomastus californiensis were found in the four habitats and four seasons. The density, biomass, richness index, evenness index, and diversity index of the polychaete had no significant differences among seasons but significant differences among habitats, and the dominant species of polychaete in S.

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Objective: To investigate the feasibility of modified frontolateral partial laryngectomy without tracheostomy in the treatment for early laryngeal cancer or severe atypical hyperplasia of the true vocal cord.

Methods: A retrospective analysis of 41 patients treated in the past 6 years with modified frontolateral partial laryngectomy without tracheostomy was carried out. There were 39 early laryngeal cancers of the lateral vocal cord with 34 in T1a stage and 5 in T2, and the remain 2 patients had severe atypical hyperplasia of the lateral vocal cord.

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Objective: To investigate the effects of risperidone on the polysomnography (PSG) in the patients with first-episode schizophrenia.

Methods: Twenty-five patients with first-episode schizophrenia, 13 males and 12 females, aged 29 +/- 8, underwent polysomnographic recording for 4 consecutive nights, the first night being used for acclimatization, and on the 3 rd and 4 th nights risperidone in the dose of 1.2 mg was administered before going to bed.

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Objective: To investigate the characteristics of sensory gating P50 of patients with first-episode schizophrenia.

Methods: The auditory evoked potentials P50 were recorded in 66 patients (Group Sch) with first-episode schizophrenia and 92 normal controls (Group NC) by using conditioning/testing paradigm presented with auditory double click stimuli.

Results: The value of S1-P50 of Group Sch was 3 microV +/- 2 microV, significantly lower than that of Group NC (6 microV +/- 3 microV, P <0.

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Objective: To evaluate the results of surgery for laryngeal carcinoma.

Methods: A retrospective analysis of long-term therapeutic effect was made on surgery of 105 patients with laryngeal carcinoma in the past 15 years. There were 197 males, 8 cases of female.

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