Publications by authors named "Xin-jian Lu"
Article Synopsis
- Overweight and obesity are significant global health issues, and this study examines the impact of washed microbiota transplantation (WMT) on overweight (OW) patients.
- The research involved analyzing changes in body measurements, blood sugar, blood fats, and evaluating fecal samples before and after WMT to gauge its effects.
- Results showed that WMT led to reduced body mass index (BMI) and improvements in liver fat, triglycerides, and cholesterol levels, suggesting it helps restore gut health and metabolic balance in OW patients.
Article Synopsis
- Anaemia of chronic disease (ACD) is a common type of anaemia linked to altered gut microbiota, which may influence red blood cell production.
- A study found that patients with ACD had less microbial diversity and specific butyrate-producing bacteria correlated with healthier haemoglobin levels compared to healthy individuals.
- Washed microbiota transplantation (WMT) was shown to effectively improve haemoglobin levels in ACD patients and positively altered their gut microbiota, increasing beneficial bacteria and normalizing some gut functions.
Washed microbiota transplantation improves patients with metabolic syndrome in South China.
Front Cell Infect Microbiol
December 2022
Background: Metabolic syndrome (MS) is a growing public health problem worldwide. The clinical impact of fecal microbiota transplantation (FMT) from healthy donors in MS patients is unclear, especially in southern Chinese populations. This study aimed to investigate the effect of washed microbiota transplantation (WMT) in MS patients in southern China.
View Article and Find Full Text PDFWashed microbiota transplantation improves patients with high blood glucose in South China.
Front Endocrinol (Lausanne)
October 2022
Background And Aims: Although fecal microbiota transplantation (FMT) from healthy donors has been shown to have hypoglycemic effects in animal models of diabetes, its clinical impact in patients with abnormal blood glucose metabolism is unclear, especially in southern Chinese populations. The aim of this study was to investigate the feasibility and efficacy of washed microbiota transplantation (WMT) in the treatment of abnormal blood glucose metabolism in a population in southern China.
Methods: The clinical data of patients with different indications who received 1-3 treatments of WMT were retrospectively collected.
Endothelial damage and blood brain barrier disruption contribute to ischemic stroke and brain injury. Gliptins are a novel class of treatment agents for diabetes, and recent studies have linked the use of gliptins to neuroprotection. Alogliptin is a type of orally available gliptin that was approved for clinical use by the FDA in 2013.
View Article and Find Full Text PDF[Association of CD133 expression and sensitivity of rectal cancer to preoperative radiotherapy].
Zhonghua Wei Chang Wai Ke Za Zhi
October 2012
Objective: To determine the association of CD133 expression with the sensitivity to radiotherapy among rectal cancer patients.
Methods: The clinical data of 32 rectal cancer patients was retrospectively collected for patients who received a short-term preoperative radiotherapy(5 Gy/d,×5 d) from 2008 to 2010. Pretreatment tumor biopsies were immunostained for CD133 expression.