Retrospective Analysis of Clinicopathological Characteristics of Lacrimal Gland Pleomorphic Adenoma and Mechanism of Tumorigenesis by the Imbalance Between Apoptosis and Proliferation.

BACKGROUND Lacrimal gland pleomorphic adenoma (LGPA) is the most common clinically benign epithelial tumor of the lacrimal gland and is predominantly comprised of epithelial cells and interstitial components. At present, the exact pathogenesis of LGPA remains unclear. Previous research has indicated that the occurrence of LGPA may be related to excessive cell proliferation.

Establishment of a combination scoring method for diagnosis of ocular adnexal lymphoproliferative disease.

Lymphoproliferative diseases (LPDs) of the ocular adnexa encompass the majority of orbital diseases and include reactive follicular hyperplasia (RFH), atypical lymphoid hyperplasia (ALH), and mucosa-associated lymphoid tissue lymphoma (MALToma). Lymphoid follicles (LFs) are usually observed during the histological examination of LPDs. Currently, because there is a lack of specific clinical signs and diagnostic immunohistochemical biomarkers, it is difficult for pathologists to distinguish MALToma from ocular RFH and ALH, which makes the clinical management of these conditions difficult.

[Analysis on the safety of ophthalmic artery cannulation for intra-arterial chemotherapy in 42 patients with intraocular stage retinoblastoma].

Objective: To investigate the safety of treatment with ophthalmic artery cannulation for intra-arterial chemotherapy (IAC) for children with intraocular retinoblastoma (RB).

Method: In the RB Treatment Center of General Hospital of Armed Police Forces between January 2009 and September 2011, 42 patients who were diagnosed intraocular RB and treated with ophthalmic artery cannulation for IAC, 8 patients were treated 1 circle, 31 patients were treated 2 circles and 3 patients were treated 3 circles (total, 96 times). Each month had IAC once.

[Clinical analysis of 14 cases of congenital orbital fibrosis].

Objective: The purpose of this study was to show the clinical and imaging characteristics in patients with congenital orbital fibrosis.

Methods: A retrospective review of a series of 14 patients with congenital orbital fibrosis hospitalized in Institute of Orbital Disease during 2005 to 2009 have been characterized. Patients aged from 3 months to 18 years old, the median age was 7 years old, 6 cases (43%) were male.

[Study on peripheral blood T lymphocyte cell membrane in thyroid associated ophthalmopathy by using atomic force microscopy].

Objective: To study the cell membrane of T-lymphocytes in thyroid associated ophthalmopathy (TAO) by using atomic force microscopy (AFM).

Methods: Case-control study. Forty-two patients were selected as the subjects, and divided into two groups: acute stage (18) and stationary stage (24) ones on the basis of symptom.

[Preliminary observations of embolization treatment of orbital varices with Glubran 2 acrylic glue].

Objective: To evaluate the outcome of embolization via orbital surgical exposure for a series of orbital varices.

Methods: This study is a retrospective review of 28 patients (28 eyes, 11 men, 17 women) which were diagnosed as orbital varix from March to December in 2007, in the Institute of Orbital Diseases. Patient's age ranged from 11 to 54 years old, mean 32 years old.

[Diagnosis and management of orbital metastatic tumors].

Objective: To evaluate the type, clinical features and diagnostic methods of orbital metastatic tumors.

Methods: In a retrospective study, the records of 30 consecutive cases with orbital metastatic tumors as confirmed by pathologic examination were analyzed with special attention to the epidemiology, clinical manifestations and imaging findings.

Results: Most orbital metastatic tumors in China originated from the breast, followed, in order, by the lung and liver.

[Analysis of the results of surgical management of orbital osteoma].

Objective: To analyze the results and skill of surgical management of orbital osteoma retrospectively.

Methods: It was a retrospective case series. Nineteen cases of orbital osteoma (the diagnosis was confirmed by surgical and pathological studies) were analyzed retrospectively in the present study.

[The features of pathology and immunohistochemistry in orbital meningiomas].

Objective: To study the biological characteristics of orbital meningiomas using histological and immunohistochemistrical analysis.

Methods: 19 specimens taking from orbital meningiomas were included in the study. HE staining was used for histology analysis and the immunohistochemistry was applied to demonstrate the expression of Vimentin, EMA, Ki-67, p53 in the tissue of orbital meningiomas.

[Retrospectively analysis of diagnosis and treatment of the orbital neurilemomas].

Objective: To evaluate the diagnosis and surgery of orbital neurilemoma.

Methods: Thirty-eight patients with pathologically confirmed orbital neurilemomas were analyzed retrospectively. The age of the patients ranged from 9 years to 69 years.

[Study on ultrasonic extraction techniques of flavonoids in Chrysanthemum morifolium].

Objective: To optimize the ultrasonic extraction condition for flavonoids from Chrysanthemum morifolium.

Method: The extraction rate of flavonoids optimized condition (ethanol concentration, ultrasonic time, solvent quantity and extraction times) was determined by orthogonal design. UV-Spectrophotometry was used for the determination.

[Study on extraction technology for extract and flavonoids in Chrysanthemum morifolium by orthogonal design].

Objective: To ascertain extraction technology condition for extract and flavonoids from Chrysanthum morifoliwn.

Method: The optimizing ultrasonic extraction condition on the basis of extractive yield and flavonoids were determined by orthogonal design.

Result: The order of factors which affected the flavonoid extraction was extraction times > ethanol concentration > ultrasonic time > solvent quantity.