Publications by authors named "Xin-hua Qiang"

Objective. To systematically review the efficacy and potential immunomodulatory effect of ulinastatin combined with thymosin α1 (UTI) for sepsis. Design.

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This study aimed to investigate the clinical features of urosepsis and to raise awareness of this problem. Of the 112 sepsis patients enrolled, 36 were identified as having urosepsis. The bacteria involved in the infection leading to urosepsis included Escherichia coli, Proteus species, Enterococcus species, Klebsiella species, other Gram-positive cocci, and Pseudomonas aeruginosa.

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Article Synopsis
  • The study aimed to understand how the immune system reacts during severe sepsis and how certain treatments might help.
  • 91 patients with severe sepsis were divided into four groups: one received special blood treatments, another got a medication called thymosin alpha(1), a third group got both treatments, and the last group just received standard care.
  • Results showed that the patients who died within 28 days had much higher levels of certain immune signals compared to those who survived, indicating that their immune systems were really off balance.
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Objective: To discuss the effect of continuous blood purification (CBP), thymosin alpha1 and combined therapy on cellular immunity in patients with severe sepsis.

Methods: Ninety-one patients, age over 18 years, suffering from severe sepsis with Marshall score over 5, admitted to the intensive care unit (ICU) from June, 2004 to October, 2007, were randomly divided into four groups. The patients in control group (24 cases) were treated with classical Surviving Sepsis Campaign (SSC) therapy, those in CBP group (22 cases) were treated with continuous renal replacement therapy (CRRT) or molecular adsorbent recirculating system (MARS) in the first 3 days.

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