[Clinical analysis of curative resection with hemihepatectomy for advanced hilar cholangiocarcinoma].

Objective: To investigate the superiority of curative resection with hemihepatectomy in treatment of hilar cholangiocarcinoma and the strategy to lower the incidence of complications and mortality.

Methods: The clinical data of 50 patients with hilar cholangiocarcinoma who underwent surgical procedures in Peking University School of Oncology from January 1998 to May 2006 were retrospectively analyzed.

Results: Forty-one patients (56.

Radiofrequency ablation of hepatocellular carcinoma: long-term outcome and prognostic factors.

Purpose: To investigate the efficacy of radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC), and the prognostic factors for post-RFA survival rate.

Methods: From 1999 to 2006, 266 patients with 392 HCCs underwent ultrasound guided RFA treatment. They were 216 males and 50 females, average age 59.

[Clinicopathological features of solid pseudopapillary tumor of the pancreas].

Objective: To elucidate the clinicopathological features of solid pseudopapillary tumor (SPT) of the pancreas.

Methods: Eight patients with SPT of the pancreas admitted from August 1996 to March 2005 were retrospectively analyzed.

Results: All the 8 patients were female with an average age of 25.

[Spleen-preserving distal pancreatectomy in treatment of solid-pseudopapillary neoplasm].

Objective: To investigate the feasibility and safety of spleen-preserving distal pancreatectomy with conservation of the splenic arteries and veins in treatment of benign neoplasms of distal pancreas.

Methods: Four patients with solid-pseudopapillary neoplasm, 1 males and 3 females, aged 30 (17 - 37), underwent laparotomy. The distal pancreas with tumor was cut.

Solid pseudopapillary tumor of the pancreas: report of 8 cases in a single institution and review of the Chinese literature.

Background: Solid pseudopapillary tumor of the pancreas (SPTP) is a rare disease with a low-grade malignant potential. In recent years, the incidence has been increasing. No consensus has been reached regarding diagnostic or therapeutic strategies.

Preliminary study on proteomics of gastric carcinoma and its clinical significance.

Aim: To explore the preliminary identification of serum protein pattern models that may be novel potential biomarkers in the detection of gastric cancer.

Methods: A total of 130 serum samples, including 70 from patients with gastric cancer and 60 from healthy adults, were detected by surface-enhanced laser desorption and ionization time-of-flight mass spectrometry (SELDI-TOF-MS). The data of spectra were analyzed by Biomarker Patterns Software (BPS).

[Long term (5 years) outcome of radiofrequency ablation for hepatocellular carcinoma in 256 cases].

A total of 267 patients with hepatocellular carcinoma underwent ultrasound-guided radiofrequency ablation (RFA) in Peking University School of Oncology between 1999 and 2005 (421 RFA sessions). Among them, 254 patients were candidates for RFA treatment and the selective criteria were: (1) the greatest diameter of tumor View Article and Find Full Text PDF

[Abnormal expression of Thy-1 as a novel tumor marker in lung cancer and its prognostic significance].

Objective: The purpose of this study was to investigate the expression of Thy-1 immunohistochemically in different lung tumors and its prognostic significance in non-small cell lung cancer (NSCLC) cases. We also evaluate relationship between Thy-1 and p53 expression status so as to find any clue about the mechanism.

Methods: In this study, we used anti-Thy-1/CD90 antibody to detect the expression pattern of Thy-1 in different lung tumor sections, which were embedded in paraffin blocks.

[Standard treatment of liver malignancies with radiofrequency ablation].

Objective: To investigate the role of standard treatment with ultrasound-guided radiofrequency ablation (RFA) in improving the treatment level of liver malignancies.

Methods: 302 patients with 476 liver malignancies were treated with established protocol and adjuvant measures and subjected to efficiency analysis. In the 302 patients, 181 had 282 hepatocellular carcinomas (HCC) with a mean diameter of 4.

[Radiofrequency ablation of recurrent hepatocellular carcinoma after hepatectomy].

Objective: To assess the efficiency and safety of radiofrequency ablation (RFA) of recurrent hepatocellular carcinoma (RHCC) after hepatectomy and to investigate efficacy of RFA for patients with early and late phase recurrence, separately, setting 1 year as the cut-off between the early and late phases.

Methods: A total of 42 patients with 77 RHCC and a history of hepatic resection for hepatocellular carcinoma (HCC) underwent ultrasound-guided percutaneous radiofrequency ablation in our department and entered this study (RHCC group). The average diameter of RHCC was (3.

[Efficacy of radiofrequency ablation of 343 patients with hepatic tumor and the relevant complications].

Objective: To investigate the treatment efficacy of radiofrequency ablation (RFA) of hepatic tumors and the relevant complications.

Methods: A total of 343 patients with 778 hepatic tumors underwent ultrasound-guided RFA (582 procedures). There were 212 cases of hepatic cellular carcinoma (HCC) with 448 tumors, and the average largest diameter was 4.

Stomach-interposed cholecystogastrojejunostomy: a palliative approach for periampullary carcinoma.

Aim: For patients of periampullary carcinoma found to be unresectable at the time of laparotomy, surgical palliation is the primary choice of treatment. Satisfactory palliation to maximize the quality of life with low morbidity and mortality is the gold standard for a good procedure. Our aim is to explore such a procedure as an alternative to the traditional ones.

[Expression of wild type and variant estrogen receptors in human hepatocellular carcinoma].

Objective: To investigate the expression of wild type estrogen receptor (wER) and the exon-5 deleted ER (variant ER, vER) in human hepatocellular carcinoma (HCC) samples, and thereafter analyze the possibility of HCC treatment by endocrine therapy.

Methods: The mRNA expressions of wER and vER were analysed from 28 cases of HCC by RT-PCR. The expression of ER at the protein level was detected by immunohistochemistry (IHC).

Clinical features, diagnosis, treatment and prognosis of multiple primary colorectal carcinoma.

Aim: To investigate the clinical features, diagnosis, treatment and prognosis of multiple primary colorectal carcinomas (MPCC).

Methods: A retrospective analysis of 37 patients with MPCC from 1974 to 1998 was carried out.

Results: The incidence of MPCC was 2.

[Mathematical protocol for radiofrequency ablation of liver tumors and its clinical application].

Objective: To develop a preoperative protocol for ultrasonography-guided percutaneous radiofrequency ablation (RFA) on liver tumors larger than 3.5 cm in diameter based on mathematical models and clinical experience, and to evaluate its ablated effect compared to the previous non-math method.

Methods: One hundred and twenty-five patients with 80 primary and 55 secondary liver tumors (4.