[The changes of HIF-1α and AMPKα2 expression levels during skeletal muscle blunt injury recovery].

Objective: To explore the possible biological mechanisms of skeletal muscle injury recovery by observing the changes of AMP-activated protein kinase α2 (AMPKα2) and hypoxia inducible factor-1α (HIF-1α) expression levels of rats in the skeletal muscle blunt injury recovery process.

Methods: Six of the 48 male Wistar rats was randomly selected as the normal control group. The blunt injury model was set up by injuring the hind legs of remaining 42 rats with heavy objects.

[Blood oxygen and lactate concentrations in skeletal muscles during exercise].

Objective: To study the relationship between blood lactate and blood oxygenation in human skeletal muscle.

Method: Using a portable tissue oximeter based on Near-Infrared Spectroscopy (NIRS), concentration of HbO2, blood lactate and blood volume were measured non-invasively and continuously when the subjects were doing incremental exercise on a bicycle ergometer.

Result: As the intensity of exercise was increased, blood lactate concentration, blood volume in tissue increased, while concentration of HbO2 decreased.