[Research progress in health impact of traffic noise].

Traffic noise pollution problem is increasingly emerging with the rapid development of urban traffic. Researchers have paid close attention to the health effects of traffic noise. This review has summarized the recent research progress in the health effects of traffic noise both at home and abroad.

[Preventive effects of sound insulation windows on the indoor noise levels in a street residential building in Beijing].

Objective: To evaluate the preventive effects of sound insulation windows on traffic noise.

Methods: Indoor noise levels of the residential rooms (on both the North 4th ring road side and the campus side) with closed sound insulation windows were measured using the sound level meter, and comparisons with the simultaneously measured outdoor noise levels were made. In addition, differences of indoor noise levels between rooms with closed sound insulation windows and open sound insulation windows were also compared.

[Comparison of respiratory diseases and symptoms among school-age children in areas with different levels of air pollution].

Objective: To compare the differences of children's health in different area, and to confirm if the prevalence of respiratory diseases and symptoms among children are closely associated with the air pollution.

Methods: A cross-sectional study was conducted in an urban area A and a suburban area B with different levels of air pollution in Beijing. Using a cluster sampling method, we recruited 4 564 children from 3 primary schools in urban A and 4 primary schools in suburban B.

[Concentrations of fine particulate matters and ultrafine particles and influenced factors during winter in an area of Beijing].

Objective: To study the concentrations of fine particulate matters and ultrafine particles and influenced factors during winter in an area of Beijing.

Methods: Real-time monitoring of particles' mass and number concentrations were conducted in an area of Beijing from February 7(th) to 27(th), 2013. At the same time, the meteorological data were also collected from the Beijing meteorological website.

[Effects of silver ion of silver nanoparticles on gap junctional intercellular communication of human skin cells].

Objective: To further investigate the effects of silver ion (Ag+) dissolved from silver nanoparticles (AgNps) on gap junctional intercellular communication (GJIC) between HaCaT cells.

Methods: In this study, 20 000×g of 1 g/L AgNps suspension were centrifuged at 4 °C for 2 h, then the supernatant was collected as Ag(+) stock solution and measured by inductively coupled plasma mass spectrometry (ICP-MS); GJIC was detected by the scrape loading/dye transfer assay; connexin 43 (Cx43) protein and mRNA level were estimated by Western-blot and RT-PCR, respectively.

Results: Different concentrations of Ag(+) (0.

[Long-term effects of air pollution on the occurrence of respiratory symptoms in adults of Beijing].

Objective: To investigate the long-term effects of air pollution on prevalence of respiratory symptoms in adults, in Beijing.

Methods: A cross-sectional study was conducted in an urban area and a suburban area with different levels of air pollution in October 2008, in Beijing. Respiratory symptoms were investigated by a standard questionnaire from the American Thoracic Society (ATS-DLD-78-A) in 9 052 adults who had lived there for at least two years.

[Systemic oxidative stress induced by intratracheal instilling with PM10 in rats].

Objective: To observe the oxidative stress of serum, lung and heart tissues in rats caused by PM10.

Methods: In the study,24 male Wistar rats weighed 320-360 g were randomly divided into four groups, including one saline control group and three PM10 exposed groups. PM10 was administered to the exposed groups by intratracheal instillation at the doses of 3.

[The comparison of the indoor environmental factors associated with asthma and related allergies among school-child between urban and suburban areas in Beijing].

Objective: To study the indoor environmental factors associated with the prevalence of asthma and related allergies among school children.

Methods: A cluster sampling method was used and the ISAAC questionnaire was conducted. A total of 4612 elementary students under Grade Five of 7 schools were enrolled in the survey for the impact of indoor environmental factors on the prevalence of asthma and related allergies in several urban and suburban schools of Beijing.

[Short-time effects of inhalable particles and fine particles on children's lung function in a district in Beijing].

Objective: To study short-term effects of PM10 (particulate matter of aerodynamic diameter <10 microm) and PM2.5 (particulate matter of aerodynamic diameter <2.5 microm) on children's lung function in one district in Beijing.

[Pollutions of indoor fine particles in four types of public places and the influencing factors].

Objective: To study the levels of pollutions caused by fine particulate matter (PM(2.5)) in the public places and investigate the possible influencing factors.

Methods: A total of 20 public places in four types such as rest room in bath center, restaurant, karaoke bars and cyber cafe in Tongzhou district in Beijing were chosen in this study; indoor and outdoor PM(2.

[Effects of nanoscale titanium dioxide on intercellular gap junction communication in human lung fibroblasts].

Objective: To investigate the effects of nanoscale titanium dioxide (Nano-TiO(2)) on gap junctional intercellular communication (GJIC) between human lung fibroblasts.

Methods: Human lung fibroblasts were exposed to two different sizes Nano-TiO(2) (25 nm and 80 nm) for 24 hours at the concentrations of 0, 10, 20, 40 and 80 mg/L, respectively. The GJIC between cells was measured by using fluorescence redistribution after photobleaching (FRAP) assay.

[Relationship between 5,10-methylenetetrahydrofolate reductase genetic polymorphism and arsenic metabolism].

Objective: To study the relationship between 5,10-methylenetetrahydrofolate reductase(MTHFR) genetic polymorphism and arsenic metabolism and the role of folate in it.

Methods: Forty-three individuals who were exposed to arsenic more than 0.05 mg/L in well water were chosen and the vein blood and morning urine was collected; The MTHFR C677 polymorphism was analyzed by PCR-RFLP method ; Urinary inorganic and methylated arsenic were speciated by high performance liquid chromatography combined with hydride-generation atomic fluorescence spectrometry; Microbiological assay was used to estimate serum folate.

[Effects of the inhalable particle (PM10) on secretion of inflammatory factors in human lung fibroblasts and mouse alveolar macrophage cell].

Objective: To study the effects of PM10 and the concentrated culture suspension of RAW264.7 cells treated with PM10 on the secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin-6(IL-6) and interleukin-8(IL-8) in the human lung fibroblasts( HLF).

Methods: PM10 were collected during heating period in the urban area of Beijing.

[Analysis and spatial description to correlative factors on food hygiene appeal and food poison in restaurants of city zone in Qingdao].

Objective: To study some factors that affected food poison and appeals in restaurants which were hidden danger on the cards.

Methods: Data on food hygiene events from 2002 to 2004 in restaurants of 14 blocks which were located in the important city zone of Qingdao were collected and studied. The spatial distribution was conducted by means of Geographic Information System (GIS).

[Effect of PM2.5 collected during the dust and non-dust periods on the viability and gap junctional intercellular communication in human lung fibroblasts].

Objective: To investigate the effects of PM2.5 collected during the dust and non-dust periods on the viability and gap junctional intercellular communication (GJIC) in human lung fibroblasts.

Methods: Human lung fibroblasts were treated with PM2.

[Study on the relationship between methylene tetrahydrofolate reductase gene (677C-->T) mutation and skin lesions in endemic arsenic poisoning].

Objective: Methylene tetrahydrofolate reductase (MTHFR) is the key enzyme in folate metabolism. We examined whether single nucleotide 677 C-->T mutation in the MTHFR gene could affect the occurrence of skin lesions in endemic arsenic poisoning.

Methods: Fifty individuals with arsenic-induced skin lesions were identified as cases, and 35 individuals without skin lesions from the same village were selected as controls.