Publications by authors named "Xin-Zhuo Zhan"
Qiling Baitouweng Tang (QLBTWT) is a traditional clinical formula for treating diffuse large B-cell lymphoma (DLBCL), but its molecular action is not fully understood. This research is utilized in silico analysis and liquid chromatography tandem mass spectrometry (LC‒MS/MS) to identify the active constituents of QLBTWT with anti-DLBCL properties and their targets. The study identified 14 compounds, including quercetin, naringenin, and astilbin, as potentially effective against DLBCL.
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- Xiao-Ai Jie-Du decoction (XAJDD) is traditionally used to treat diffuse large B-cell lymphoma (DLBCL) with varying prescriptions tailored to patients' conditions.* -
- The study aimed to identify the core ingredients of XAJDD and understand how they work against DLBCL using data mining and in silico modeling.* -
- The core formula includes six herbs, and key components like astibin and quercetin were found to significantly inhibit DLBCL cell proliferation and promote apoptosis, helping to reveal the treatment's molecular mechanisms.*