Publications by authors named "Xin-Yue Chang"

Article Synopsis
  • - Human defensin 5 (HD5) plays a crucial role in protecting the host by exhibiting antibacterial and antiviral properties, as well as inhibiting tumor growth and regulating immune responses.
  • - Despite its beneficial functions, HD5 may also have cytotoxic and proinflammatory effects, highlighting the complexity of its role in the body.
  • - The review focuses on understanding HD5's functions in host defense and the potential modifications to enhance its biological activity for clinical applications.
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Diflubenzuron is widely used as a benzoylurea insecticide, and its impact on human health should not be underestimated. Therefore, the detection of its residues in food and the environment is crucial. In this paper, octahedral Cu-BTB was fabricated using a simple hydrothermal method.

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Vibrio mimicus (V. mimicus) is a pathogen causing serious vibriosis in aquatic animals. Hepcidin and β-Defensin1 are two important antibacterial peptides (AMPs) with broad-spectrum antibacterial activity in fish.

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Background: Intestinal microbiota is a novel drug target of metabolic diseases, especially for those with poor oral bioavailability. Nuciferine, with poor bioavailability, has an anti-hyperlipidemic effect at low dosages.

Purpose: In the present study, we aimed to explore the role of intestinal microbiota in the anti-hyperlipidemic function of nuciferine and identify the key bacterial targets that might confer the therapeutic actions.

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