polysacharin inhibits hepatocellular carcinoma-like phenotypes in a murine HCC model through repression of M2 polarization of tumour-associated macrophages.

Context: polysaccharin (APS), an extract of Schischk, exerts antitumor effects in hepatocellular carcinoma (HCC).

Objective: This study investigated the mechanism of action of APS in HCC.

Materials And Methods: Tumour-associated macrophages (TAMs) were treated with APS (0, 8, 16 mg/mL) for 24 h.