Publications by authors named "Xin-Yao Feng"
Article Synopsis
- The Dog10K project sequenced genomes from 1,987 canids, including 1,611 dogs of 321 breeds, to study genetics related to domestication and health.
- The analysis identified over 48 million genetic variants and highlighted that most breeds exhibit strong genetic clustering, with German Shepherds showing notable genetic similarities with various breeds.
- This extensive dataset enhances understanding of canine genetics and can be used as a reliable reference for future genetic studies, with all data now publicly accessible.
Growth hormone (GH) is an important hormone released by the pituitary gland that plays a key role in the growth and development of organisms. In our study, TargetScan analysis and the dual luciferase reporter assays were used to predict and screen for miRNAs that might act on the rat Gh1 gene, and we identified miR-543-5p. Then, the GH3 cell line and the primary rat pituitary cells were transfected with miRNA mimic, inhibitor, and siRNA.
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