Publications by authors named "Xin-Yang Song"
Accurately predicting pathological complete response (pCR) to neoadjuvant treatment (NAT) in breast cancer remains challenging due to tumor heterogeneity. This study enrolled 2279 patients across 12 centers and develops a novel multi-modality model integrating longitudinal magnetic resonance imaging (MRI) spatial habitat radiomics, transcriptomics, and single-cell RNA sequencing for predicting pCR. By analyzing tumor subregions on multi-timepoint MRI, the model captures dynamic intra-tumoral heterogeneity during NAT.
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- The study investigates how intestinal epithelial dopamine D2 receptors (IEC DRD2) affect autoimmune diseases of the central nervous system (CNS), particularly in a model of multiple sclerosis.
- Female mice lacking the Drd2 receptor in their intestinal epithelial cells showed reduced CNS inflammation and slower disease progression, while activating IEC DRD2 made the condition worse.
- The research also found changes in gut microbiota composition, specifically lower levels of Lactobacillus, and identified a potential for sex-specific treatments for CNS autoimmune diseases based on these findings.
Chinese herbal medicine for infertility with anovulation: a systematic review.
J Altern Complement Med
December 2012
The aim of this systematic review is to assess the effectiveness and safety of Chinese herbal medicine (CHM) in treatment of anovulation and infertility in women. Eight (8) databases were extensively retrieved. The Chinese electronic databases included VIP Information, CMCC, and CNKI.
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