Efficacy of combined orthodontic-periodontic treatment for patients with periodontitis and its effect on inflammatory cytokines: A comparative study.

Introduction: In this study, we aimed to investigate the efficacy of combined orthodontic-periodontic treatment in the treatment of patients with periodontitis and its effects on the levels of inflammatory cytokines.

Methods: A total of 117 patients with periodontitis were randomly assigned to the basic group (receiving basic periodontic treatment, n = 58) and the combined group (receiving combined orthodontic-periodontic treatment, n = 59). In addition, 52 healthy people without periodontal disease were selected as the normal group.

[Monitoring of farmland drought based on LST-LAI spectral feature space].

Farmland drought has the characteristics of wide range and seriously affecting on agricultural production, so real-time dynamic monitored has been a challenging problem. By using MODIS land products, and constructing the spectral space of LST and LAI, the temperature LAI drought index (TLDI) was put forward and validated using ground-measured 0-10 cm averaged soil moisture of Ningxia farmland. The results show that the coefficient of determination (R2) of both them varies from 0.

[New index for soil moisture monitoring based on deltaT(s)-albedo spectral information].

Monitoring soil moisture by remote sensing has been an important problem for both agricultural drought monitoring and water resources management. In the present paper, we acquire the land surface temperature difference (deltaT(s)) and broadband albedo using MODIS Terra reflectance and land surface temperature products to construct the deltaT(s)-albedo spectral feature space. According to the soil moisture variation in spectral feature space, we put forward a simple and practical temperature difference albedo drought index (TDADI) and validate it using ground-measured 0-10 cm averaged soil moisture of Ningxia plain The results show that the coefficient of determination (R2) of both them varies from 0.

Mineralocorticoid receptor expression in human venous smooth muscle cells: a potential role for aldosterone signaling in vein graft arterialization.

Experimental studies have suggested a role for the local renin-angiotensin-aldosterone system in the response to vascular injury. Clinical data support that aldosterone, via activation of the mineralocorticoid receptor (MR), is an important mediator of vascular damage in humans with cardiovascular disease. In mineralocorticoid-sensitive target tissue, aldosterone specificity for MR is conferred enzymatically by the cortisol-inactivating enzyme 11β-hydroxysteroid-dehydrogenase-2 (11βHSD2).

Angiotensin II and tumor necrosis factor-alpha upregulate survivin and Kruppel-like factor 5 in smooth muscle cells: Potential relevance to vein graft hyperplasia.

Background: Survivin (SVV) is a unique inhibitor of apoptosis protein (IAP) that regulates both apoptosis and mitosis. Recent work suggests that SVV plays a critical role in the vascular injury response, but the molecular pathways remain unclear.

Methods: We examined the expression of SVV and the transcription factor, KLF5, in human venous smooth muscle cells (VSMC) by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) and Western blot analysis after treatment with angiotensin II (Ang II) or tumor necrosis factor-alpha (TNF-alpha).

Regulation of vein graft hyperplasia by survivin, an inhibitor of apoptosis protein.

Objective: Survivin (SVV) is an inhibitor of apoptosis protein (IAP) that is upregulated in cancer and has recently been implicated in vascular injury. We sought to investigate the role of SVV in vein graft hyperplasia.

Methods And Results: Adenoviral constructs expressing a dominant-negative (AdT34A) and wild-type (AdWT) SVV were used.

Survivin expression is up-regulated in vascular injury and identifies a distinct cellular phenotype.

Objectives: The healing response to vascular injury is characterized by neointimal thickening. Proliferation and phenotypic transformation of vascular smooth muscle cells (SMCs) have been implicated in this process. We sought to investigate the role of survivin, a dual regulator of cell proliferation and apoptosis, in lesion formation after diverse forms of vascular injury.

Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids.

Vascular smooth muscle cell (SMC) migration and proliferation contribute to neointimal hyperplasia and restenosis after vascular injury. The epoxyeicosatrienoic acids (EETs), which are products of cytochrome P450 (CYP) epoxygenases, possess vasodilatory, antiinflammatory, and fibrinolytic properties. To determine whether these compounds also possess antimigratory and antiproliferative properties, we stimulated rat aortic SMCs with either 20% serum or platelet-derived growth factor (PDGF-BB, 20 ng/mL).