Theaflavin protects chondrocytes against apoptosis and senescence regulating Nrf2 and ameliorates murine osteoarthritis.

Oxidative stress-mediated excessive apoptosis and senescence of chondrocytes are the main pathological alterations in the osteoarthritis (OA) development. The protective effects of theaflavin (TF), a common group of polyphenols in black tea, against many degenerative diseases by attenuating oxidative stress are well reported. Nevertheless, its role in the OA treatment is still scantily understood.

The acromion-greater tuberosity impingement index: A new radiographic measurement and its association with rotator cuff pathology.

Purpose: Several radiographic parameters describe humeral head coverage by the acromion. We describe a new radiographic measurement, the acromion-greater tuberosity impingement index (ATI), and its ability to predict rotator cuff pathology.

Methods: The ATI was measured with magnetic resonance imaging (MRI) and X-ray analysis in 83 patients with rotator cuff pathology and 76 patients with acute rotator cuff tears.

[Twenty years follow-up: the correlation between sleep apnea syndrome and cerebrovascular disease].

Objective: To explore the correlation between obstructive sleep apnea syndrome (OSAS) and cerebrovascular disease (CVD).

Methods: A cohort of 1868 people was screened for OSAS, and followed from November 1989 to November 2009. Annual medical examinations including blood pressure, blood fat, serum glucose, electrocardiogram and chest x-ray were performed.