[Effect of exogenous ATP on NLRP3 inflammasome activation in gingival fibroblasts cells].

Purpose: To investigate exogenous ATP-dependent activation of NLRP3 inflammasome and interleukin-1β ( IL-1β) secretion in P.gingivalis infected and heat-killed P.gingivalis induced gingival fibroblasts cells ( hGFs) in vitro.

[Expression of a DNA fragment encoding the active domain of human TNF related apoptosis inducing ligand in pichia pastoris].

Human tumor necrosis factor-related apoptosis-inducing ligand(TRAIL) is a member of the tumor necrosis factor (TNF) family of ligands which has been reported in 1995. The TRAIL protein induces apoptosis of certain types of target cells, such as transformed cells that include but are not limited to cancer cells and virus-infected cells but the normal cells. It is a type II transmembrane protein and the extracellular domain of TRAIL is the functional domain in induction of cell apoptosis.