Controlling the concentration of drugs in pharmaceutical products is essential to patient's safety. In this study, a simple and sensitive HPLC method is developed to quantitatively analyze capsaicin in collagen sponge. The capsaicin from sponge was extracted for 30 min with ultrasonic wave extraction technique and methanol was used as solvent.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
February 2014
This study was to investigate the permeability and absorbability of capsaicin cubosome across abdominal skin of the SD rats in vitro. Diffusion of capsaicin cubosome and cream was performed with the modified Franz diffusion cell technique. The capsaicin cubosome showed no enhancement of skin permeation within 24 hours.
View Article and Find Full Text PDFAsian Pac J Cancer Prev
April 2015
Published studies have evaluated associations between the MDM2 SNP309T>G polymorphism and bladder cancer susceptibility. However, these generated inconsistent results. The aim of the present investigation was to quantify the strength of association between MDM2 SNP309T>G polymorphism and bladder cancer risk by conducting a meta-analysis.
View Article and Find Full Text PDFObjective: To evaluate the predictive values of Tokuhashi score, revised Tokuhashi score and Tomita score systems for life expectancy and treatment options in patients with spinal metastasis.
Methods: From February 1996 to January 2009, spinal operations in 104 cases with spinal metastasis were performed in our hospital. There were 65 males and 39 females, with an average of 53.
Zhonghua Wai Ke Za Zhi
February 2010
The objectives of this paper were to look into the possible incidence of obvious soft tissue extension from Langerhans' cell histiocytosis (LCH) of the spine in children and to evaluate the effects of chemotherapy for those patients. Eighteen patients with histopathological diagnosis of LCH were reviewed and nine with obvious paravertebral soft tissue extension were included in this study. Soft tissue extension was involved in the spinal canal and/or around the vertebral body in eight cases and posterior involvement was prevalent in one case.
View Article and Find Full Text PDFObjective: To investigate the veracity of cortical somatosensory evoked potential (CSEP) and the influencing factors of manipulation of CSEP monitoring during the operation for cervical spondylitic myelopathy (CSM).
Methods: Sixty-eight CSM patients, 45 males and 23 females, aged 52.3, underwent CSEP monitoring at the ulnar, median, and posterior tibial nerves.