Interesting mycoparasites and gen. et sp. nov. (Hypocreales, Polycephalomycetaceae) from Yunnan Province, China.

A novel genus, was introduced to accommodate , based on a multigene phylogenetic analysis and its distinct morphological characteristics. Maximum likelihood (ML) and Bayesian inference analyses (BI) of ITS, SSU, LSU, , , and sequence data shown that formed an independent lineage nested between and . Morphologically, is distinguished from by the presence of a white subiculum on the stromata of Ophiocordycepscf.

Wulingshen, the massive sclerotia used as traditional Chinese medicine, is produced by multiple species.

Wulingshen, massive sclerotia, was originally reported from Chengdu Plain in western Sichuan of China for medicinal application. is commonly connected to these massive sclerotia produced within abandoned underground macrotermitine termite nests. We sequenced 54 Wulingshen samples procured from traditional Chinese medicine markets in Chengdu Plain and connected them to six different species: , two species newly described herein- and , and two species that are known only as sclerotia thus far.

Xylastriasan A, a new cytochalasan from the fungus Xylaria striata.

Xylastriasan A (1), a new cytochalasan alkaloid with a rare 5/6/6/5/6 pentacyclic skeleton, and ergosterol (2) were isolated from the ethanol extract of fruiting bodies of the fungus Xylaria striata. Their structures were determined by analysis of their spectroscopic data. Compound 1 exhibited weak cytotoxic activity against HEPG2, B16 and A549 cell lines with IC values of 93.

[Optimization of submerged culture conditions for Xylaria striata mycelium].

Objective: To establish the optimum submerged culture condition of Xylaria striata mycelium.

Methods: One-factor-at-a-time method and orthogonal experiment design were applied and the dry weight of mycelium was tested for evaluation the biomass of the growth of Xylaria striata mycelium.

Results: The results from one-factor-at-a-time experiments showed that maltose, glucose or corn powder could be used as the best carbon source and the optimum nitrogen source was soybean powder.

Xylaria coprinicola, a new species that antagonizes cultivation of Coprinus comatus in China.

The species known in China as the chicken-claw fungus is described as a new species, Xylaria coprinicola. This species is known as an antagonist of cultivation of the edible mushroom Coprinus comatus. Stromata of X.

[Kinetic model for exopolysaccharides (EPS) of Ganoderma lucidum in batch fermentation].

The synthetic characteristic of extracellular polysaccharide (EPS) of Ganoderma lucidum performed in batch fermentation was studied. The result showed that the production EPS was partially growth-associated. The cell dry weight (CDW) and EPS reached 15.

[The expression of migration inhibitory factor in peripheral blood mononuclear cell and its correlation with disease activity in systemic lupus erythematosus].

Objective: To investigate the change of macrophage migration inhibitory factor (MIF) mRNA expression in peripheral blood mononuclear cell (PBMC) and serum MIF and its correlation with disease active index in patients with systemic lupus erythematosus (SLE).

Methods: MIF mRNA expression of PBMC and serum MIF in patients with active and inactive SLE was measured by reverse transcriptase-polymerase chain reaction and enzyme-linked immunosorbent assay, respectively. The correlations of serum MIF with SLE disease active index, serum ds-DNA antibody, ANA, C3, C4 and IgG were examined.