Publications by authors named "Xin-Ru Cheng"
Background: To investigate the relationship between the OPRM1 gene A118G polymorphism and intracranial hemorrhage (ICH) in premature infants and identify the relevant genes in disease occurrence.
Methods: In the present case study analysis, polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to detect the genotype and allele frequencies of the OPRM1 gene All8G single nucleotide polymorphism (SNP) in a case group of premature infants with ICH (n=167) and a control group of premature infants (n=163) without ICH.
Results: In the case group, 73 (43.
Article Synopsis
- This study assesses NT-proBNP levels alongside spontaneous breathing trials to predict ventilator weaning success in preterm infants with respiratory distress syndrome (RDS).
- Out of 88 infants, 63 passed the breathing trials, but 16 were later reintubated, indicating weaning failure, which was linked to lower gestational age and higher NT-proBNP levels.
- The research concludes that NT-proBNP is a reliable predictor of weaning failure, suggesting its measurement before trials could enhance weaning outcomes.
[Investigation on factors related to pyelic separation in early newborns].
Zhongguo Dang Dai Er Ke Za Zhi
October 2012
Article Synopsis
- The study examines the connection between pyelic separation and factors like gestational age, body weight, and sex in 320 newborns, showing varied incidence rates among groups.
- Results indicate that boys have a significantly higher occurrence of pyelic separation (37.8%) compared to girls (22.2%), with no significant differences in location between sexes.
- Findings reveal that the anteroposterior diameter (APD) is positively correlated with gestational age and body weight, while the incidence of pyelic separation decreases with increasing birth weight, except in heavier infants.
Article Synopsis
- The study investigates the link between Val279Phe SNPs in the PAF-AH gene and intracranial hemorrhage in preterm infants.
- A case-control design compared 58 preterm infants with hemorrhage and 65 without, using PCR to analyze genetic variations.
- Results showed significant differences in genotype and allele frequencies between groups, suggesting that specific SNPs may increase the risk of intracranial hemorrhage.
[Serum NT-proBNP levels in neonates with severe asphyxia and the effects of nalmefene on the NT-proBNP levels].
Zhongguo Dang Dai Er Ke Za Zhi
November 2010