[Expression of candidate tumor suppressor gene N-Myc downstream-regulated gene 2 in colon cancer].

Objective: To analyze the expression level of candidate tumor suppressor gene N-Myc downstream-regulated gene 2 (NDRG2) in human colon cancer.

Methods: Thirty samples of colon cancer tissues with matched normal colon tissues were collected. The NDRG2 mRNA level was detected by semi-quantitive RT-PCR and the NDRG2 protein level was examined by Western blot and immunohistochemistry.

[Induction of apoptosis of HepG2 cells by NDRG2].

Aim: To explore the induction of HepG2 cells by NDRG2 gene.

Methods: Human NDRG2 gene was obtained by RT-PCR. Sequence analysis proved that sequence of NDRG2 gene was correct.