Publications by authors named "Xin-Liang Fu"
Article Synopsis
- SBDS outbreaks caused by NGPV have been noted in China since 2015, with NGPV being a single-stranded DNA virus likely transmitted vertically.
- The study found that NGPV boosts cGAS mRNA expression but weakens the induction of IFN-β, inhibiting downstream interferon-stimulated genes and interfering with the immune response.
- VP1, a viral protein, plays a crucial role in inhibiting IFN-β expression, while its truncated forms lack this capability, indicating that NGPV impacts the host's innate immune response through modulation involving IRF7.
The mitochondrial quality control system is crucial in maintaining cellular homeostasis during environmental stress. Granulosa cells are the main cells secreting steroid hormones, and mitochondria are the key organelles for steroid hormone synthesis. The impact of the mitochondrial quality control system on granulosa cells' steroid hormone synthesis and survival under heat stress is still unclear.
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- * High concentrations of LPS downregulate specific genes related to cell proliferation and steroid hormone synthesis, while also increasing p27kip1 expression, indicating cell cycle alterations.
- * Elevated temperatures further worsen LPS's inhibitory effects on gene expression related to proliferation and steroid hormone production, highlighting a complex interaction between heat and LPS in duck GCs.
Stocking density critically affects the growth and subsequent performance of animals in modern poultry production. This study investigated the effects of stocking density on ovarian development, ovarian maturation, and the mRNA expression of key genes in the reproductive axis during the rearing period of Shan-ma ducks. The experiments involved 180 healthy 7-wk-old Shan-ma ducks and randomly divided into low stocking density (LSD; n = 30, density = 5 birds/m), medium stocking density (MSD; n = 60, density = 10 birds/m) and high stocking density groups (HSD; n = 90, density = 15 birds/m), for rearing.
View Article and Find Full Text PDFResveratrol, a natural antioxidant, anti-inflammatory plant extract, was found to have a protective effect in poultry subjected to heat stress. In this study, we strove to characterize resveratrol on intestinal of duck exposed to acute heat stress and investigate the underlying mechanism. A total of 120 Shan-ma ducks (60 days old) were randomly divided into 2 groups.
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- Granulosa cells (GCs) are crucial for follicle development, and this study examines how heat stress at 41°C and 43°C affects their growth and steroid production in ducks.
- Using RNA sequencing, the research identified changes in gene expression, revealing that heat stress leads to an increase in GCs blocked in the G1 phase and a decrease in genes important for follicle progression.
- A total of 241 differentially expressed genes were found, with key findings including the activation of heat shock proteins and CXC chemokines, and downregulation of collagenases, suggesting potential molecular mechanisms for reduced egg production in ducks during heat stress.