Identification and validation of a five-gene prognostic signature based on bioinformatics analyses in breast cancer.

Background: This study aimed to identify prognostic signatures to predict the prognosis of breast cancer (BRCA) patients based on a series of comprehensive analyses of gene expression data.

Methods: The RNA-sequencing expression data and corresponding BRCA patient clinical data were collected from the Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GEO) datasets. Firstly, the differently expressed genes (DEGs) related to prognosis between tumor tissues and normal tissues were ascertained by performing R package "limma".

Carbothermal redox reaction in constructing defective carbon as superior oxygen reduction catalysts.

Defects can greatly promote the catalytic activity of a carbon-based electrocatalyst due to charge redistribution of its electroneutral π-conjugated structure. However, it is still a huge challenge to introduce enough defects into carbon-based materials to improve their catalytic activity. Herein, we report a new method for defect generation by the pyrolysis of the sulfur-nitrogen-containing coordination polymer [Zn(ptt)] (ptt = 1-phenyl-1-tetrazole-5-thiol).

[BaCl] Cations Directed Perovskite-like Polar Metal Formate Frameworks {[BaCl][M(HCO)]} (M = Mn, Co, and Mg): Microwave-Assisted Synthesis, Structures, and Properties.

Novel 3D metal formate frameworks {[BaCl][M(HCO)]} (M = Mn for , Co for , and Mg for ) were successfully assembled via microwave-assisted synthesis. The complexes are rare coordination polymers crystallized at space group 4 with the polar point group . In the structure, the M ions are bridged by two types of - formate in forming a 3D framework, and additional formates coordinate to the unsaturated sites of the M ions in the framework, giving an anionic M-formate net.

Body Mass Index May Positively Correlate with Bone Mineral Density of Lumbar Vertebra and Femoral Neck in Postmenopausal Females.

Background: Our study aimed to explore the relationship between body mass index (BMI) and bone mineral density (BMD) of lumbar vertebra and femoral neck in postmenopausal females.

Material/methods: From September 2012 to September 2014, 236 healthy postmenopausal females who underwent physical examinations at the Women & Children's Health Care Hospital of Linyi were enrolled into our study. These subjects were divided into 3 groups: underweight group, normal weight group, and overweight group.