Publications by authors named "Xin-Dang Wang"
Article Synopsis
- The study aimed to explore the relationship between KIR gene polymorphism and susceptibility to systemic lupus erythematosus (SLE) in patients.
- Researchers analyzed the KIR genes of 62 SLE patients and 61 healthy controls using a specialized PCR method.
- Results showed significant differences in KIR gene frequencies between the two groups, suggesting a potential link between KIR gene variations and SLE, prompting further investigation.
[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
February 2007
Article Synopsis
- The study focused on the relationship between the killer cell immunoglobulin-like receptor (KIR) gene polymorphism and leukemia susceptibility among patients in northern Hans.
- Analysis of 50 leukemia patients and 60 healthy controls revealed significant differences in the frequencies of specific KIR genes, with certain genes like KIR 3DL1 and 2DL1 being notably lower in leukemia patients.
- The findings suggest a potential negative correlation between the presence of specific KIR genes and the development of leukemia, indicating the importance of KIR gene variation in understanding the disease.
[Distribution features of HLA-DRB1 allele frequencies in normal cord blood donors of 3 438 Shandong Hans].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
June 2004
The objective of the study was to research the distribution features of HLA-DRB1 alleles in Shandong Hans' population and explore the possibility of finding the cord blood donor of HLA-DR matched to perform the stem cell transplantation for more patients from larger region of China and even other areas in the world. The subjects of the study were drawn from 3 438 Shandong Hans donors in Shandong Umbilical Cord Blood Bank and were tested by PCR-SSP technique for HLA-DR low resolution typing. The result indicated that the most prevalent five alleles of HLA-DRB1 locus were DRB1 * 15 (0.
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