Identification of miRNAs as prognostic factors for esophageal squamous cell carcinoma.

The prognostic value of microRNAs for esophageal squamous cell carcinoma (ESCC) is still not be well identified. The microRNA expression profiles of 119 paired ESCC tissue samples and para-carcinoma tissues from GEO database under accession number of GSE43732. A mutation information based feature selection method was applied to identify the discriminative microRNAs between paired ESCC tissues and para-carcinoma tissues.

Overexpression of violaxanthin de-epoxidase gene alleviates photoinhibition of PSII and PSI in tomato during high light and chilling stress.

A tomato (Lycopersicon esculentum) violaxanthin de-epoxidase gene (LeVDE) was isolated. The deduced amino acid sequence of LeVDE showed high identities with violaxanthin de-epoxidase in other plant species. RNA gel blot analysis showed that the mRNA accumulation of LeVDE in the wild-type (WT) was regulated by diurnal rhythm and temperature.

Overexpression of sweet pepper glycerol-3-phosphate acyltransferase gene enhanced thermotolerance of photosynthetic apparatus in transgenic tobacco.

In order to investigate the relationship between the lipid composition in thylakoid membrane and thermostability of photosynthetic apparatus, tobacco transformed with sweet pepper sense glycerol-3-phosphate acyltransferase (GPAT) gene were used to analyze the lipid composition in thylakoid membrane, the net photosynthetic rate and chlorophyll fluorescence parameters under high temperature stress. The results showed that the saturated extent of monogalactosyldiacylglycerol (MGDG), sulfoquinovosyldiacylglycerol, digalactosyldiacylglycerol and phosphatidylglycerol in thylakoid membrane of transgenic tobacco T(1) lines increased generally. Particularly, the saturated extent in MGDG increased obviously by 16.

[Treatment effect of percutaneous vertebroplasty combined with interventional chemotherapy on vertebral metastases].

Background & Objective: Vertebral metastasis is a common manifestation of patients with advanced cancer without effective treatment. This study was to explore treatment value and efficacy of percutaneous vertebroplasty (PVP) combined with interventional chemotherapy on vertebral metastases.

Methods: Seventy-five patients with vertebral metastases (42 men, 33 women; aged 31-76 years) were divided into 2 groups: 39 were treated by PVP combined with chemotherapy (VPCC group), and 36 were treated by PVP alone (VP group).

[Effect of preoperative intra-arterial chemotherapy on apoptosis and p53 expression of gastric cancer].

Background & Objective: Regional chemotherapy is charactized by a high drug concentration in tumor tissues and slight side-effects. Some significant histopathological changes were observed in the patients with gastric carcinoma treated by selective intra-arterial infusion chemotherapy before operation. The aim of this study was to investigate the effect of preoperative intra-arterial chemotherapy on apoptosis and p53 expression in human gastric cancer and its clinical significance.