Publications by authors named "Xin-Ce Huang"
Background: Sarcopenia is a nutrition-related disease and has a profound effect on the long-term overall survival (OS) of patients with gastric cancer. Its diagnostic criterion is critical to clinical diagnosis and treatment. However, previous research reported widely differing sarcopenia prevalence due to different criteria.
View Article and Find Full Text PDFA simple method for the determination of Bosutinib in rat plasma by UPLC-MS/MS.
J Chromatogr B Analyt Technol Biomed Life Sci
November 2015
In this work, a simple, sensitive and fast ultra performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for the quantitative determination of bosutinib in rat plasma. Plasma samples were processed with a protein precipitation. The separation was achieved by an Acquity UPLC BEH C18 column (2.
View Article and Find Full Text PDFDetermination of trifolirhizin in rat plasma by UPLC: Application to a pharmacokinetic study.
J Chromatogr B Analyt Technol Biomed Life Sci
May 2015
Article Synopsis
- A new analytical method using ultra-performance liquid chromatography (UPLC) was developed to detect trifolirhizin in rat plasma, with pirfenidone as the internal standard.
- The method demonstrated good linearity between 25-1000 ng/mL and had a lower limit of quantification of 25 ng/mL, with high precision and accuracy in measurements.
- Stability studies confirmed trifolirhizin's resilience under various storage conditions, and the method was effectively used in a pharmacokinetic study after oral administration to rats.