Publications by authors named "Xin-Can Liu"

Article Synopsis
  • - The novel SARS-CoV-2 is responsible for COVID-19, impacting over 17 million people globally, prompting the need for updated diagnosis and treatment guidelines for clinicians.
  • - A working group of experts developed evidence-based recommendations by reviewing literature to address 29 key management questions related to chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19.
  • - They issued 34 statements, including 6 strong recommendations, 14 weak recommendations, 3 weak recommendations against, and 11 ungraded consensus statements, covering various aspects such as diagnostic methods and potential treatments.
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Clinical trials are the source of evidence. ClinicalTrials.gov is valuable for analyzing current conditions.

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This study investigated the interaction among valsartan (VAL), TGF-β pathways, and long non-coding RNA (lncRNA) cardiac hypertrophy-related factor (CHRF) in doxorubicin (DOX)-induced heart failure (HF), and explored their roles in DOX-induced HF progression. HF mice models in vivo were constructed by DOX induction. The expression of CHRF and TGF-β1 in hearts was detected, along with cardiac function, caspase-3 activity, and cell apoptosis.

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