Publications by authors named "Xin Zhe Yu"

Article Synopsis
  • The study focuses on primary gallbladder neuroendocrine carcinomas (GB-NEC), aiming to summarize their characteristics, effective treatments, and factors affecting patient prognosis.
  • A total of 55 patients who underwent surgical resection were analyzed, revealing that those who had R resection had significantly better overall survival than others.
  • Key factors associated with reduced survival included being 60 years or older, having carcinoid syndrome, and undergoing non-R resection, emphasizing the importance of complete surgical removal as the primary treatment approach.
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Background: Previous researches in pancreatic cancer demonstrated a negative correlation between secreted protein acidic and rich in cysteine (SPARC) expression in primary tumor and survival, but not for SPARC expression in lymph node. In the present study, we aimed to evaluate the SPARC expression in various types of tissues and its impact on patients' prognosis.

Methods: The expression of SPARC was examined by immunohistochemistry in resected pancreatic cancer specimens.

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Objective: To establish a serum protein fingerprint model for prediction of liver metastasis from colorectal cancer by SELDI-TOF-MS analysis, and to determine the differentiatial proteins associated with the metastatic liver cancers.

Methods: Data were collected from the Department of General Surgery in Zhongshan Hospital. A group of patients with colorectal cancer (CRC) without liver metastasis (n = 36) and another group with liver metastasis (n = 36) were included in this study.

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Objective: To establish serum proteome fingerprinting predictive models and search for proteins associated with colorectal cancer.

Methods: Thirty-six randomly selected colorectal cancer patients and 36 cases with hernia or gall bladder diseases scheduled for elective operation were enrolled as cancer group and control group respectively. Peripheral venous blood samples were collected before the operations.

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