Publications by authors named "Xin Yu Zhu"

Sleeve lobectomy has solidified its position as a preferred alternative to pneumonectomy due to its significant advantage in preserving lung function, whereas right lower lobe sleeve lobectomy remains relatively uncommon because of the higher technical challenge. With the development of minimally invasive technology and experience acquired over the years, robot-assisted thoracoscopic surgery (RATS) has shown progress and distinct advantages compared to the traditional thoracotomy and video-assisted thoracoscopic surgery (VATS) approach. Owing to its 3D vision, bendable wrist joints, and tremor filtration capabilities, this surgical technique exhibits great advantages in complex thoracic operations demanding for reconstructive procedures compared to traditional thoracoscopic surgery.

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  • The study focuses on understanding the mechanisms behind the cholangiocellular phenotype (CCA) in hepatocellular carcinoma (HCC), particularly the roles of specific cell types in tumor progression.
  • Utilizing single-cell RNA sequencing, researchers identified a unique subset of senescent endothelial cells (CD34CLDN5 ECs) that promote tumor growth by secreting IGF2, which attracts mesenchymal stem cells (MSCs) to the tumor microenvironment.
  • The interaction between these senescent ECs and MSCs was shown to enhance cancer malignancy, revealing potential targets for therapeutic intervention in HCC.
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Lactococcus muris was published in Cell Host & Microbe in November 2022 and validated in validation list no. 213 in October 2023. Lactococcus intestinalis was published in Antonie van Leeuwenhoek in May 2023 and validated in validation list no.

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Introduction: The domestication of edible mushrooms, including Flammulina filiformis, offers valuable insights into the genetic changes driven by artificial selection. Understanding these changes is crucial for uncovering the mechanisms behind genome evolution in domesticated mushrooms.

Objectives: This study aims to investigate the population structure, genetic diversity, and domestication-related genomic changes in F.

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The composition of T cell subsets and tumor-specific T cell interactions within the tumor microenvironment (TME) contribute to the heterogeneity observed in breast cancer. Moreover, aberrant tumor metabolism is often intimately linked to dysregulated anti-tumor immune function of T cells. Identifying key metabolic genes that affect immune cell interactions thus holds promise for uncovering potential therapeutic targets in the treatment of breast cancer.

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Two new species and are described and illustrated, based on morphological characteristics and molecular phylogenetic analysis. Two new records, and from Thailand, are also reported. is characterized by small basidiomata, stipe equal with an enlarged base, and nearly subclavate, pale pink to light orange.

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Central nervous system Infections (CNSIs) is a disease characterized by complex pathogens, rapid disease progression, high mortality rate and high disability rate. Here, we evaluated the clinical value of metagenomic next generation sequencing (mNGS) in the diagnosis of central nervous system infections and explored the factors affecting the results of mNGS. We conducted a retrospective study to compare mNGS with conventional methods including culture, smear and etc.

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Although GaN is a promising candidate for semiconductor devices, degradation of GaN-based device performance may occur when the device is bombarded by high-energy charged particles during its application in aerospace, astronomy, and nuclear-related areas. It is thus of great significance to explore the influence of irradiation on the microstructure and electronic properties of GaN and to reveal the internal relationship between the damage mechanisms and physical characteristics. Using a combined density functional theory (DFT) and molecular dynamics (AIMD) study, we explored the low-energy recoil events in GaN and the effects of point defects on GaN.

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is the largest genus in the Russulales and is widespread throughout the world. Almost all species are known to be ectomycorrhizal with high ecological and edible values, and some are lethal poisonous. In this study, four new species belonging to the subgenus crown clade are identified based on morphological and phylogenetic evidence from the Xizang Autonomous Region and other provinces of China.

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Whipple's disease is a chronic systemic infectious disease that mainly affects the gastrointestinal tract. In some cases, Tropheryma whipplei can cause infection at the implant site or even throughout the body. In this study, we collected alveolar lavage fluid samples from patients with Tropheryma whipplei from 2020 to 2022, and retrospectively analyzed the clinical data of Tropheryma whipplei positive patients.

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Chronic non-communicable diseases (CNCDs) pose a significant public health challenge. Addressing this issue, there has been a notable breakthrough in the prevention and mitigation of NCDs through the use of antioxidants and anti-inflammatory agents. In this study, we aim to explore the effectiveness of Eupatorium adenophora Spreng leaves (EASL) as an antioxidant and anti-inflammatory agent, and its potential applications.

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The application of biomarkers to study the molecular composition of soil organic matter (SOM) can be used to analyze the source and degradation of SOM and reveal the stability mechanism of soil organic carbon (SOC) at the molecular level. In order to further clarify the effects of different land use patterns (farmland, grassland, and forest) on the molecular composition of SOM, the changes in molecular composition of organic matter (free lipids, cutin, suberin, and lignin) on a global scale were studied using a meta-analysis method. The results showed that there were significant differences in the molecular composition of organic matter under different land use patterns.

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  • Ectopic superior parathyroid glands can be found in rare locations such as the tracheoesophageal groove, leading to hyperparathyroidism that may require surgical removal.
  • Traditional surgical methods involve more invasive approaches, while new minimally invasive techniques like thoracoscopic resection are emerging as effective alternatives.
  • A case study demonstrated that video-assisted thoracoscopic surgery (VATS) not only effectively treated an ectopic parathyroid gland but also reduced complications and costs associated with the procedure.
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  • * Researchers collected seventy-eight specimens from ten provinces in China and performed both molecular phylogenetic analysis and morphological examinations to identify the species.
  • * Eleven species were recognized, including five newly discovered ones, mainly from the Xizang Autonomous Region, highlighting their unique adaptation to this specific habitat and contributing to the understanding and conservation of fungal diversity.
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Introduction: Psittacosis is a zoonosis caused by Chlamydia psittaci, the clinical manifestations of Psittacosis range from mild illness to fulminant severe pneumonia with multiple organ failure. This study aimed to evaluate the clinical characteristics of Chlamydia psittaci infection diagnosed based on metagenomic next-generation sequencing(mNGS), as well as the risk factors affecting the progress of Chlamydia psittaci infection, in order to improve the effect of therapeutics.

Methods: We retrospectively analyzed the clinical data of patients infected with chlamydia psittaci in the First Affiliated Hospital of Nanchang University from January 2021 to December 2021.

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  • - The study aimed to evaluate how image features and radiomics combined with machine learning can assess liver function in cirrhotic patients using Gd-EOB-DTPA-enhanced MRI.
  • - A total of 123 cirrhotic patients underwent MRI, and various imaging metrics were analyzed to develop a machine learning model (using support vector machine) to classify liver function.
  • - The findings showed that the radiomics-based model outperformed traditional imaging metrics, achieving high accuracy (89.19%) and sensitivity (95.45%) in distinguishing different levels of liver function based on the Child-Pugh classification.
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The performance of multipath transmission control protocol (MPTCP) subflow through the enhancement mechanism of the MPTCP communication is improved. When dealing with multiple MPTCP subflows occupying the same transmission path, critical issues such as selection and optimization of multipath, and efficient scheduling of available multiple tracks are effectively addressed by incorporating the technology called software defined network (SDN) that is constructed based on four key parameters, namely, network transmission bandwidth, transmission paths, path capacity, and network latency. Besides, critical equipment such as the network physical device layer and SDN controller are integrated with the four parameters.

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  • Anaplastic lymphoma kinase negative anaplastic large cell lymphoma (ALK-ALCL) is a rare and aggressive type of peripheral T-cell lymphoma, predominantly affecting lymph nodes and occasionally other tissues, with a higher prevalence in males.
  • A case of primary cutaneous ALK-ALCL was presented, showing diverse cellular characteristics and confirmed through imaging techniques, with no recurrence observed over a six-month follow-up.
  • The condition typically appears as red-brown skin lesions and requires differentiation from systemic ALCL, with prognosis influenced by the lesion's location and severity, emphasizing the importance of imaging for accurate diagnosis and treatment.
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Background: There is consensus that postoperative adjuvant therapy is not recommended in patients with stage 1a non-small cell lung cancer (NSCLC). Meanwhile, it is still controversial whether postoperative adjuvant chemotherapy is recommended for NSCLC patients with T2aN0M0 (stage 1b). In some patients with stage 1b NSCLC without pleural invasion, tumor diameter was measured between 3 and 4 cm by preoperative imaging and less than 3 cm by postoperative pathology specimens.

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In recent years, the synthesis of C-aryl glycosides hrough C-H functionalization has attracted extensive attention of organic synthesis chemists due to its steps and atomic economy. In this concept, we systematically summarizes the synthesis of C-aryl glycosides with diverse regioselectivity and diastereoselectivity from the perspective of C-H arylation of glycosides and C-H glycosylation of arenes. It can be found that a series of recently developed C-H glycosylation reactions have higher site-selectivity and diastereomeric selectivity than Friedel-Crafts glycosylation reaction.

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Background: In the treatment of peripheral early-staged lung cancer and benign lesions, segmentectomy and wedge resection are both reliable treatment methods. It is debatable that how much pulmonary function will be lost after different sublobar resection in the treatment of early-staged deep-located peripheral NSCLC (non-small cell lung cancer). The purpose of this study was to explore postoperative pulmonary function changes of sublobar resection in enrolled patients with non-subpleural peripheral nodules.

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A novel method of one-step co-cultivation and harvesting of microalgae and fungi, for efficient starch wastewater treatment and high-value biomass production was developed. By combination of Aspergillus oryzae and Chlorella pyrenoidosa, nutrients in wastewater could be converted to useful microbial biomass, while the wastewater was purified. Moreover, the microalgae C.

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