Efficient Fluoride Removal Using a CeO/Attapulgite (ATP) Composite.

In this study, a CeO/attapulgite (ATP) composite was synthesized via a straightforward hydrothermal method to efficiently remove excess fluoride from water. The structural and surface properties of the synthesized adsorbent were systematically characterized using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The fluoride adsorption capacity of the CeO/ATP composite was systematically evaluated, reaching a maximum of 47.

Evaluation of salivary ceruloplasmin for the diagnosis of Wilson's disease.

The serum ceruloplasmin assay is the most commonly used test for diagnosing Wilson's disease (WD). Despite the utility of non-invasive tests for diagnosing WD, no such tests have been developed. Therefore, we aimed to identify a safe and non-invasive assay and determine the factors associated with salivary ceruloplasmin.

Discovery of a novel thiophene carboxamide analogue as a highly potent and selective sphingomyelin synthase 2 inhibitor for dry eye disease therapy.

Dry eye disease (DED) is a prevalent and intractable ocular disease induced by a variety of causes. Elevated sphingomyelin (SM) levels and pro-inflammatory cytokines were detected on the ocular surface of DED patients, particularly in the meibomian glands. Sphingomyelin synthase 2 (SMS2), one of the proteins involved in SM synthesis, would light a novel way of developing a DED therapy strategy.

Development and validation of a predictive model for the risk of symptomatic adjacent segmental degeneration after anterior cervical discectomy and fusion.

Background: To investigate the risk factors for symptomatic adjacent segment degeneration (ASD) 5 years after anterior cervical discectomy and fusion (ACDF) and develop and evaluate predictive models.

Methods: A total of 655 patients who underwent ACDF were randomly assigned to the training set ( = 393) or validation set ( = 262) at a ratio of 6:4. Independent predictors of ASD were selected by LASSO regression and logistic regression analysis.

Shell-like Ni(OH) loaded with Pd nanoparticle catalyst mediated efficient electrocatalytic upcycling of polyethylene terephthalate plastics to glycolic acid.

Electrochemical techniques offer a promising approach to achieving plastic waste recycling, particularly to address plastic pollution problems. In this study, we developed a novel Pd/Ni(OH)/NF electrocatalyst. with efficient interfacial electron transfer capability in the conversion of ethylene glycol (EG) to high-value-added glycolic acid (GA) from the hydrolyzed product of polyethylene terephthalate (PET) plastics.

Rational Design of a Quasi-Metal-Organic Framework by Ligand Engineering for Efficient Biomass Upgrading.

The electrooxidation of 5-hydroxymethylfurfural (HMF) to 2,5-furandicarboxylic acid (FDCA), a monomer for degradable bioplastic, is a promising strategy for biomass upgrade and yet requires well-designed catalysts with high efficiency and selectivity. Taking advantage of the open metal sites of metal-organic frameworks (MOFs), quasi-MOFs represent viable catalysts, but the poor designability and unpredictable structures hinder their development. In this work, a Ni-based quasi-MOF was rationally designed and synthesized by controlled ligand engineering.

Humic acid inhibits hydroxyl radical generation during oxygenation of Fe(II) on goethite surface.

The dark formation of hydroxyl radicals (•OH) by the oxidation of Fe(II) has been increasingly recognized at anoxic-oxic interface. Minerals play significant roles on oxidation of Fe(II) owing to the adsorption changed the reactivity of Fe(II). However, the impact of dissolved organic matter (DOM) on the oxidation of mineral adsorbed Fe(II) and •OH generation remains unknown.

Curculigoside exhibits multiple therapeutic efficacy to induce apoptosis and ferroptosis in osteosarcoma via modulation of ROS and tumor microenvironment.

Objective: Patients with osteosarcoma (OS) exhibit metastasis upon diagnosis, and the condition frequently acquires resistance to traditional chemotherapy treatments, failing the therapy. The objective of this research was to examine the impact of curculigoside (Cur), a key phenolic compound discovered in the rhizome of C. orchioides Gaertn, on OS cells and the surrounding tumor environment.

Catalytic ozonation of dimethyl phthalate by Ti-MCM-41 in water.

A Ti-MCM-41 mesoporous molecular sieve catalyst was prepared by a hydrothermal method. Nitrogen adsorption desorption, XRD, TEM and SEM characterization results showed that the catalyst had a large specific surface area, a regular hexagonal pore structure, and titanium doping was uniformly dispersed in MCM-41 molecular sieves. The amount of titanium doping, reaction temperature, and the initial solution pH had important effects on the catalytic ozonation of dimethyl phthalate (DMP) by Ti-MCM-41.

Mechanism of solid electrolyte interphase film formation using ethylene carbonate-based local high concentration electrolyte in sodium-ion batteries.

Sodium-ion batteries (SIBs) have the advantages of abundant resources and low cost, making them potential candidates for the next-generation large-scale energy storage technology. However, the capacity fade during cycling used in sodium-ion batteries is a major challenge. The rational design of the electrolyte is one of the ways to solve these problems.

Epitaxial Electrodeposition of Zinc on Different Single Crystal Copper Substrates for High Performance Aqueous Batteries.

The aqueous zinc metal battery holds great potential for large-scale energy storage due to its safety, low cost, and high theoretical capacity. However, challenges such as corrosion and dendritic growth necessitate controlled zinc deposition. This study employs epitaxy to achieve large-area, dense, and ultraflat zinc plating on textured copper foil.

Inhibition of cap-dependent endonuclease in influenza virus with ADC189: a pre-clinical analysis and phase I trial.

ADC189 is a novel drug of cap-dependent endonuclease inhibitor. In our study, its antiviral efficacy was evaluated in vitro and in vivo, and compared with baloxavir marboxil and oseltamivir. A first-in-human phase I study in healthy volunteers included single ascending dose (SAD) and food effect (FE) parts.

Twisted Cucurbit[14]uril-Based Supramolecular Self-Assembly Induces Fluorescence Emission of Dye Molecules for Multi-Channel Cell Imaging.

In this study, a supramolecular fluorescent material was constructed by using double-cavity twisted cucurbit[14]uril (tQ[14]) and positively charged Astrazon Pink FG (APFG) based on the non-covalent host-guest interaction for the first time. The thermodynamic parameters of the APFG@tQ[14] in aqueous solution were determined by isothermal titration calorimetry (ITC), the results indicated that the spontaneous assembly of APFG@tQ[14] is mainly driven by enthalpy. The intramolecular charge transfer (ICT) effect induced the APFG@tQ[14] probe to emit a strong orange-red fluorescence.

The comparison of uniportal versus multiportal video-assisted thoracic surgery for esophageal cancer: a propensity-weighted analysis.

Objectives: The utilization of uniportal video-assisted thoracoscopic surgery (VATS) has become prevalent, notwithstanding, there are few studies exploring its application specifically in esophagectomy.

Methods: A retrospective analysis was conducted on data collected from patients diagnosed with clinical stage T1-3/N0/M0 thoracic esophageal cancer, who underwent surgery between January 2017 and December 2020. To evaluate the outcomes, an analysis was conducted utilizing the inverse probability of treatment weighting (IPTW) method.

Supramolecular phosphorescent assemblies based on cucurbit[8]uril and bromophenylpyridine derivatives for dazomet recognition.

A bromophenylpyridine derivative (N1) was designed, synthesized, and the molecule was incorporated into the cavity of the cucurbit[8]uril (Q[8]) as a guest to form a 2:1 host-guest complex. This complex demonstrates good room temperature phosphorescence (RTP) properties in aqueous solution. The host-guest interaction and optical properties of N1@Q[8] in aqueous solution were studied by means of H NMR, ultraviolet-visible absorption spectroscopy, fluorescence spectroscopy, phosphorescence spectroscopy, scanning electron microscopy and inverted fluorescence microscopy.

Concept and framework of digital twin human geographical environment.

The human geographical environment is a comprehensive setting formed by the interaction between human activities and the geographical environment, characterized by its complexity and vulnerability. Applying the digital twin method to create a new research model in a human geographical environment holds significant academic and practical value. This approach helps avoid disturbances in the real environment, deeply explores complex issues, and optimizes solutions for real-world geographical problems.

Wolfberry (Lycium barbarum) glycopeptide attenuates dopaminergic neurons loss by inhibiting lipid peroxidation in Parkinson's disease.

Background: Parkinson's disease (PD) is a common neurodegenerative disorder characterized clinically by motor dysfunction due to gradual loss of dopaminergic neurons in the nigrostriatal system. Currently, medications such as levodopa preparations, offer only temporary symptomatic relief without preventing neuronal loss or halting disease progression. In traditional Chinese medicine (TCM), a particular type of wolfberry or goji berry, the fruit of Lycium barbarum L.

In situ growth of bismuth oxybromide/bismuth molybdate 2D/2D Z-scheme heterojunctions with rich interfacial oxygen vacancies for photocatalytic benzylic C(sp)-H bond activation.

The selective oxidation of toluene into valuable chemicals via photocatalytic C(sp)-H bond activation represents a significant, yet challenging process. Here, the in situ construction of bismuth oxybromide/bismuth molybdate (BiOBr/BiMoO) 2D/2D Z-scheme heterojunctions featuring interface-induced oxygen vacancies (OVs) is introduced. The optimized BiOBr/BiMoO sample has a remarkable yield rate of benzaldehyde at 2134.

Itaconic acid ameliorates necrotizing enterocolitis through the TFEB-mediated autophagy-lysosomal pathway.

Excessive autophagy has been implicated in the pathogenesis of necrotizing enterocolitis (NEC), yet the molecular underpinnings of the autophagy-lysosomal pathway (ALP) in NEC are not well characterized. This study aimed to elucidate alterations within the ALP in NEC by employing RNA sequencing on intestinal tissues obtained from affected infants. Concurrently, we established animal and cellular models of NEC to assess the therapeutic efficacy of itaconic acid (ITA).

Second-shell modulation on porphyrin-like Pt single atom catalysts for boosting oxygen reduction reaction.

The first coordination shell is considered crucial in determining the performance of single atom catalysts (SACs), but the significance of the second coordination shell has been overlooked. In this study, we developed a post-doping strategy to realize predictable and controlled modulation on the second coordination shell. By incorporating a P atom into the second coordination shell of a porphyrin-like Pt SAC, the charge density at the Fermi level of Pt single atom increases, enhancing its intrinsic activity.