Publications by authors named "Xin Wei Chia"
Background: Diabetic kidney disease (DKD) is a leading cause of end-stage kidney disease and is associated with high mortality rates. The influence of routine clinical parameters on DKD onset in patients with type 2 diabetes mellitus (T2DM) remains uncertain.
Methods: In this systematic review and meta-analysis, we searched multiple databases, including PubMed, Embase, Scopus, Web of Science, and Cochrane Library, for studies published from each database inception until January 11, 2024.
Learning of adaptive behaviors requires the refinement of coordinated activity across multiple brain regions. However, how neural communications develop during learning remains poorly understood. Here, using two-photon calcium imaging, we simultaneously recorded the activity of layer 2/3 excitatory neurons in eight regions of the mouse dorsal cortex during learning of a delayed-response task.
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- The study combines deep learning and reinforcement learning (RL) to investigate how reward-based learning and decision-making function in both humans and animals.
- Researchers trained deep RL agents and mice on the same sensorimotor task, comparing the learning patterns of their neural networks.
- Findings showed that the representation of task performance in RL agents mirrored the neural activity in the posterior parietal cortex of mice, suggesting similarities between artificial and biological systems in processing complex tasks.