Publications by authors named "Xin Ran"

The wood industry's dependence on traditional petrochemical adhesives, which pose environmental and health risks, has spurred research into sustainable alternatives. Sustainable bio-based polysaccharide materials show promise due to their inherent adhesive properties, despite challenges related to mechanical weaknesses and water resistance. Inspired by the hardening mechanisms of nacre and arthropod cuticles, we have developed a novel biomimetic flame-retardant HPA/OCTS/VMT NSs-NH adhesive.

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Background And Aims: It remains uncertain whether pericoronary adipose tissue attenuation (PCATa) is associated with clinical outcome in patients with nonobstructive coronary artery disease (CAD). We aim to investigate the incremental prognostic value of PCATa beyond clinical and coronary computed tomographic angiography (CCTA) features in patients with nonobstructive CAD.

Methods: Consecutive patients with chest pain suspected of CAD referred for CCTA from January 2017 to December 2018 were prospectively included.

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Polysaccharides, key bioactive compounds derived from Chinese herbs, are increasingly recognized for their therapeutic potential in modulating gut microbiota to treat various diseases. However, their efficacy in alleviating mammary inflammation and oxidative stress and protecting the blood-milk barrier (BMB) compromised by Staphylococcus aureus (S. au) infection remains uncertain.

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  • - Recent research shows that polysaccharides can improve intestinal health, which in turn helps reduce disease progression, specifically in mastitis cases in mice.
  • - Administering a specific polysaccharide (ASP) lowered inflammation and damage caused by mastitis, but these benefits disappeared when antibiotics were used, highlighting the importance of gut microbiota.
  • - The study found that ASP boosts microbial diversity and shifts gut bacteria composition, increasing helpful metabolites while decreasing harmful ones, suggesting potential new treatment strategies for mastitis and other infections.
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  • Social network analysis has become a key tool in understanding collaborations among physicians, especially in relation to prescribing practices for older patients in Ohio.
  • The concept of homophily suggests that similar individuals (like doctors with similar prescribing habits) are more likely to connect, which can influence interventions aimed at reducing risky-prescribing behaviors.
  • By analyzing Medicare data and using advanced network modeling, the study aims to identify patterns of risky-prescribing among physicians, which could inform targeted group interventions to improve patient safety.
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  • The study examines the impact of tumor budding (TB) as a prognosis factor in stage II colorectal cancer (CRC) patients who underwent surgery, analyzing how its features relate to outcomes in postoperative chemotherapy.
  • Data from 336 patients, categorized into three TB grades (BD1, BD2, BD3), reveal that higher TB grades correlate with lower rates of recurrence-free survival (RFS) and overall survival (OS), especially highlighting BD3 patients' poor outcomes.
  • While adjuvant chemotherapy significantly benefits patients with lower TB grades (BD1/2), it does not improve survival for BD3 patients, suggesting BT's role as a crucial predictor of treatment efficacy and prognosis.
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Existing issues with bio-based adhesives, such as complex preparation processes, high energy consumption, and production costs, still need to be addressed. In our study, APTES was grafted onto microcrystalline cellulose (MCC) to generate active aminated cellulose, and then reacted with the epoxide group in glycerol triglycidyl ether (GTE) through a swelling strategy under alkaline solvent, forming a network structure via covalent cross-linking. The adhesive exhibits superior bonding performance and water-resistant property in the bonding strength test of poplar plywood, with a dry shear strength of 2.

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Risky-prescribing is the excessive or inappropriate prescription of drugs that singly or in combination pose significant risks of adverse health outcomes. In the United States, prescribing of opioids and other "risky" drugs is a national public health concern. We use a novel data framework-a directed network connecting physicians who encounter the same patients in a sequence of visits-to investigate if risky-prescribing diffuses across physicians through a process of peer-influence.

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Fluorescent probes with preferred photophysical properties have attracted considerable attention for their advantages in real-time and accurate detection of signalling molecules in living organisms. Nitric oxide (NO) is a ubiquitous cellular messenger closely associated with many physiological and pathological processes. A NO fluorescent probe, PYSNO, based on the pyridazinone (PY) scaffold with o-phenylenediamine as the receptor and thiophene (S) as the linker has been synthesized.

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Background: Hainan Island and the Leizhou Peninsula, the southernmost part of mainland China, are areas where Aedes aegypti and Ae. albopictus are sympatric and are also high-incidence areas of dengue outbreaks in China. Many studies have suggested that Aedes endogenous viral components (EVEs) are enriched in piRNA clusters which can silence incoming viral genomes.

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An infantile hemangioma is a congenital benign tumor formed by the proliferation of vascular cells during the embryonic stage. It is more common in the skin but can also occur in the mucous membranes, liver, brain and muscle. Hepatic hemangioma appears to be a benign tumor; however, it may lead to poor outcomes because of severe complications, such as high-output cardiac failure.

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Employing the Complex Adaptive System (CAS) framework, we analyzed the evolution of digitally transformed financial networks, underscoring the pivotal role of adaptation and learning among network participants. Government funds supporting banks and platforms in digital transformation prove more effective than direct subsidies to SMEs. Achieving sustainable development requires an optimal balance between investment and efficiency due to the impact of digitalization costs on constructing digital financial networks.

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Article Synopsis
  • - The text discusses two opportunistic pathogens that have shown potential for multidrug resistance and questions whether chronic infection symptoms relate to decreasing susceptibility.
  • - It presents a case study of sporotrichosis that is secondary to a specific fungal infection.
  • - It highlights that the appearance of blackish-red spots under dermoscopy can aid in the early detection and monitoring of subcutaneous fungal infections.
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Bamboo, as a renewable bioresource, exhibits advantages of fast growth cycle and high strength. Bamboo-based composite materials are a promising alternative to load-bearing structural materials. It is urgent to develop high-performance glued-bamboo composite materials.

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How to efficiently produce high performance plywood is of particular interest, while its sensitivity to moisture is overcome. This paper presents a simple and scalable strategy for the preparation of high-performance plywood based on the chemical bonding theory; a wood interfacial functionalized platform (WIFP) based on (3-aminopropyl) triethoxysilane (APTES) was established. Interestingly, the APTES-enhanced dialdehyde cellulose-based adhesive (DAC-APTES) was able to effectively establish chemically active adhesive interfaces; the dry/wet shear strength of WIFP/DAC-APTES adhesive was 3.

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Social network analysis has created a productive framework for the analysis of the histories of patient-physician interactions and physician collaboration. Notable is the construction of networks based on the data of "referral paths" - sequences of patient-specific temporally linked physician visits - in this case, culled from a large set of Medicare claims data in the United States. Network constructions depend on a range of choices regarding the underlying data.

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The World Health Organization recommends breastfeeding for 6 months, but mastitis, a common disease during lactation, presents a major obstacle to fulfilling this recommendation. Maternal nutrient intake during lactation has been shown to be related to mastitis. Therefore, this study aimed to explore the effect of hesperetin, a phytonutrient, on mastitis.

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  • - Polysaccharide-based adhesives, particularly chitosan-derived ones, present eco-friendly options but often lack strong adhesion.
  • - This study introduces a novel core-shell structure (SiO-NH@OPG) inspired by lobster anatomy, blending it with chitosan to create an effective wood adhesive (SiO-NH@OPG/CS).
  • - The new adhesive not only cures with heat but also at room temperature through water evaporation, and its unique microstructure enhances the strength and performance of wood composites.
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A Personal Health Knowledge Graph (PHKG) facilitates the efficient integration of potential diagnostic clues from patients' electronic health records with medical knowledge, establishing diagnostic reasoning paths and ensuring accurate, individually interpretable results in the diagnosis of pelvic masses.

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Background: Diagnostic errors have become the biggest threat to the safety of patients in primary health care. General practitioners, as the "gatekeepers" of primary health care, have a responsibility to accurately diagnose patients. However, many general practitioners have insufficient knowledge and clinical experience in some diseases.

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Objective: Breast cancer is a malignant tumor in the epithelial tissue of the breast gland. This study aimed to unveil the expression and clinical diagnostic value of lncRNA cervical cancer high-expressed 1 (CCHE1) in breast cancer.

Methods: CCHE1 expression in breast cancer tissues was evaluated by RT-qPCR.

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Background: Aedes albopictus is an important vector of arboviral diseases, transmitting yellow fever, dengue fever, chikungunya and Zika. Monitoring its population genetic diversity and genetic differentiation has become essential for the control of infectious disease epidemics, especially in the functional areas of ports of entry. Population genetic monitoring of Ae.

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