Primary intracranial extraskeletal myxoid chondrosarcoma: A case report and review of literature.

Background: Primary intracranial extraskeletal myxoid chondrosarcoma (EMC) is an extremely rare low- to intermediate-grade malignant soft tissue sarcoma, and only 15 cases have been reported in the literature. Due to its rarity, clinical data and research on this tumor type are extremely limited, the pathogenesis and histological origin are still unclear, and the diagnostic and standard clinical treatment strategies for intracranial EMC remain controversial and undefined.

Case Summary: We reported a case of a 52-year-old male who was admitted to the hospital with headache and dizziness for 1 mo, and his health status deteriorated during the last week.

The effects of halogen elements on the opening of an icosahedral B framework.

The fully halogenated or hydrogenated BX (X = H, F, Cl, Br and I) clusters are confirmed to be icosahedral. On the other hand, the bare B cluster is shown to have a planar structure. A previous study showed that a transformation from an icosahedron to a plane happens when 5 to 7 iodine atoms are remained [P.

Netrin-1 promotes glioma growth by activating NF-κB via UNC5A.

Gliomas, a common type of brain tumor, are characterized by aggressive infiltration, making it difficultly to cure by surgery. Netrin-1, an extracellular guidance cue critical for neuronal axon path-finding, has been reported to play an important role in cell invasion and migration in several types of cancers. However, the role of netrin-1 in glioma remains largely unknown.

Serum Gamma-glutamyl Transferase Levels Predict Functional Outcomes after Aneurysmal Subarachnoid Hemorrhage.

Objective: We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population.

Methods: A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined.

Salvianolic Acid B Ameliorates Lipopolysaccharide-Induced Albumin Leakage from Rat Mesenteric Venules through Src-Regulated Transcelluar Pathway and Paracellular Pathway.

Lipopolysaccharide (LPS) causes microvascular barrier disruption, leading to albumin leakage from microvessels resulting in a range of disastrous sequels. Salvianolic acid B (SalB) is a major water-soluble component derived from Salvia miltiorrhiza. Previous studies showed its potential to attenuate microvascular barrier dysfunction, but the underlying mechanism is not fully understood.

Perioperative acute myocardial infarction increases mortality following noncardiac surgery.

Objective: To provide insight into diagnosis, treatment, and prevention of perioperative myocardial infarction (PMI).

Design: The authors retrospectively analyzed PMI characteristics in patients undergoing noncardiac surgery and identified risk factors for death.

Setting: An affiliated teaching hospital with about 1500 beds.

[Application of sedation with a low dose of dexmedetomidine during intrathecal anesthesia in elderly patients].

Objective: To explore the feasibility and safety of sedation with a low dose of dexmedetomidine (DEX) during intrathecal anesthesia in the elderly patients.

Methods: Thirty elderly patients were randomly divided into the DEX group (n = 15) and the control group (n = 15). There were 13 males and 17 females with a mean age of 77 years old (range: 65 - 89 years old).

[A comparison of remifentanil versus sufentanil with target-controlled infusion in combined inhalation anesthesia for surgical patients: effects on hemodynamics and postoperative recovery].

Objective: To compare the effect of remifentanil versus sufentanil with target-controlled infusion in combination with inhalation anesthesia for surgical patients on the parameters of hemodynamics and postoperative recovery.

Methods: Forty ASA I-II patients aged 18 - 65 years old with BMI (body mass index) < 30, undergoing colectomy or pedical screw interfix were enrolled. Upon the approval of institutional Ethics Committee, they were randomized to receive remifentanil or sufentanil at a target plasma concentration of 3 ng/ml and 0.

[The application of remifentanil-propofol and remifentanil-midazolam analgesia for choledochofiberscopic dilatation of bile duct].

Objective: To evaluate the safety and efficacy of remifentanil-propofol and remifentanil-midazolam analgesia for choledochofiberscopic dilatation of bile duct.

Methods: 95 patients undergoing choledochofiberscopic dilatation of bile duct were reviewed, 43 of which were dealt with remifentanil-propofol (PR) and 52 with remifentanil-midazolam (MR). After medication, changes of HR, MAP, RR and SPO(2) were observed.

Minimum effective local anesthetic dose of intrathecal hyperbaric ropivacaine and bupivacaine for cesarean section.

Background: Intrathecal anesthesia is commonly used for cesarean section. Bupivacaine and ropivacaine have all been used as intrathecal drugs. The minimum effective local anesthetic dose (MLAD) of intrathecal ropivacaine for non-obstetric patients has been reported.

[Effect of remifentanil on propofol pharmacokinetics with target controlled infusion in elderly patients].

Objective: To investigate the effects of remifentanil administered by target-controlled infusion (TCI) with different plasma concentration and time on pharmacokinetics of propofol in elderly patients.

Methods: Thirty-two ASA I-II patients (65-82 years old) undergoing elective lower abdominal operations were divided into 4 groups randomly: TCI propofol combined with epidural block (group A, n=8); TCI remifentanil with plasma concentration 4 μg/L and propofol (group B, n=8); TCI remifentanil with plasma concentration 7 μg/L and propofol (group C, n=8); and TCI propofol and remifentanil (plasma concentration 4 μg/L) with infusion time longer than 4 hours (group D, n=8). Propofol was infused by target-controlled infusion with plasma concentration 3 mg/L in the 4 groups.

[The relationship between systemic inflammatory response syndrome and severity of acute pancreatitis combined with plateau erythrocythemia].

Objective: To explore the relationship between systemic inflammatory response syndrome(SIRS) and severity of acute pancreatitis combined with plateau erythrocythemia in the high altitude.

Methods: A retrospective analysis on the clinical data which involved acute pancreatitis combined with plateau erythrocythemia (n = 40) and without plateau erythrocythemia (n = 40) admitted from September 2006 to September 2009 was conducted. According to the unified standards, these cases were divided into plateau erythrocythemia group and no plateau erythrocythemia group.

[The feasibility of Supreme laryngeal mask airway in gynecological laparoscopy surgery].

Objective: To explore the safety, efficacy and side effect of Supreme laryngeal mask airway (LMA) used in gynecological laparoscopy.

Methods: From Oct. 2009 to Apr.

[The effects of hydroxyethyl starch on lipopolysaccharide-induced endothelial injury in rat mesenteric venules].

Objective: To investigate the effect of hydroxyethyl starch (HES, 130/0.4) on lipopolysaccharide (LPS)-induced endothelial injury in rat mesenteric venules.

Methods: Thirty-six Wistar rats weighing 200 - 250 g were randomly divided into 3 groups, n = 12 for each group.

[Investigation and analysis of status in simulation education of anesthesiology of China].

Objective: To investigate the status of simulation education of anesthesiology in China.

Methods: Five hundreds questionnaires were mailed to chairmen of department of anesthesiology in teaching hospitals in 29 provinces and autonomous regions in China. The retrieved questionnaires and data were processed and analyzed with statistics.

[The changes and significance of multiple organ functions in acute pancreatitis patients under hypoxic condition on plateau].

Objective: To explore characteristics of the pathogenesis and progression of the acute pancreatitis (AP) in high altitude and the relationship between AP and plateau erythrocythemia.

Methods: Retrospective analysis of the clinical data of AP was conducted for 103 inpatients who were admitted during 2003 and 2005 to the People's Hospital of Qinghai Province, including 12 cases of AP complicated with plateau erythrocythemia and 91 cases of AP no complicating plateau erythrocythemia. The patients were divided into a group of 57 cases living in high altitude (>3 000 m) and 46 patients in lower altitude group (<2 200 m).

Clinical evaluation of target controlled infusion system for sufentanil administration.

Background: Sufentanil target controlled infusion (TCI) provides stable analgesia, better hemodynamic control than a bolus injection of intravenous anesthetics, anticipated recovery and improved quality of anesthesia during perioperative period. This study evaluated the accuracy and feasibility of TCI system for sufentanil at high concentrations in Chinese surgical patients.

Methods: Twelve low risk adult patients undergoing elective surgery under general anesthesia were included in this study.

[Incidence of peri-operative anxiety and depression in patients and of risk factors].

Objective: Our study investigate the peri-operative incidence of depression and anxiety of patients undergoing general anesthesia, and assesses the relationship between peri-operative characteristics with anxiety and depression.

Methods: Demographic, clinical data and HADS score were collected before and after surgery. Analysis all the data with SPSS 10.

Two-stage analysis of pharmacokinetics of sufentanil administered by target-controlled infusion in Chinese patients.

Background: Sufentanil is a suitable choice for target-controlled infusion (TCI) because of its shorter context-sensitive half-time. The current study was to estimate the pharmacokinetics of sufentanil TCI in Chinese patients using the two-stage analysis.

Methods: Twelve adult patients with American Society of Anesthesiologists (ASA) physical status I or II undergoing elective surgery under general anesthesia were included.

The effects of cardiopulmonary bypass on the number of cerebral microemboli and the incidence of cognitive dysfunction after coronary artery bypass graft surgery.

Background: Postoperative cognitive dysfunction (POCD) can be a debilitating complication after coronary artery bypass graft (CABG) surgery. Cerebral microemboli during cardiopulmonary bypass (CPB) are believed to be an important etiologic factor of POCD. In this study, we examined whether avoidance of CPB with "off-pump" surgery reduces the number of cerebral microemboli and the incidence of POCD after CABG surgery in Chinese population.

[Incidence and influential factors of post-operative nausea and vomiting following gynecological surgery: analysis of 492 cases].

Objective: To investigate the incidence and influential factors of post-operative nausea and vomiting (PONV) following gynecologic surgery so as to provide guideline effective for clinical management.

Methods: The clinical data of 492 qualified consecutive female patients who had undergone gynecological surgery were analyzed. Univariate analysis and multivariate logistic regression were applied to examine the relations between the perioperative variables and occurrence of PONV within 6 h or 24 h following gynecologic procedures.

[Epidural analgesia in latent phase of labor: effects on length of labor and mode of delivery].

Objective: To compare the outcome of ropivacaine plus sufentanil for patient-controlled epidural analgesia between nulliparous women presenting in latent and active labor.

Methods: 360 nulliparous parturients were randomized according to cervix dilation. Latent group (cervix dilation < 3 cm) received 0.

Effect of flumazenil on bispectral index monitoring in unpremedicated patients.

Background: Flumazenil is an imidazobenzodiazepine that promptly reverses via competitive inhibition the hypnotic/sedative effects of benzodiazepines on gamma-aminobutyric acid receptors. Endogenous benzodiazepine ligands (endozepines) were isolated in urine, cerebrospinal fluid, and breast milk of women who had not received benzodiazepines. The bispectral index (BIS), an electroencephalographically derived parameter widely used for monitoring the effects of anesthetic/hypnotic drugs, was shown to correlate to various conditions that could influence electroencephalography.