Publications by authors named "Xin Hua Ou"
Background: During 2012, Changsha experienced a large outbreak of hand, foot, and mouth disease (HFMD), resulting in 25,438 cases, including 42 severe cases and eight deaths.
Methods: Seven hundred and forty-six clinical specimens were collected from hospital-based surveillance for HFMD in 2012. The detection and genotyping of enterovirus were performed by real-time RT-PCR and sequencing of the VP1 regions; phylogenetic analysis was performed based on the VP1 sequences.
Surveillance of influenza virus during 2010-2012 in Changsha, China.
Southeast Asian J Trop Med Public Health
March 2014
The objective of this study was to examine the circulating influenza viruses in Changsha, China, during 2010-2012. Nasopharyngeal specimens were collected from persons with influenza-like illness (ILI) who presented for care at two hospitals. Of 2,955 patients tested, 278/(9.
View Article and Find Full Text PDF[Risk related to the transmission of H5N1 subtype avian influenza virus in the environment of poultry markets in Changsha, China].
Zhonghua Liu Xing Bing Xue Za Zhi
August 2012
Objective: To investigate the risk of H5N1 subtype avian influenza virus (AIV) transmission in the poultry market environment in Changsha city. H5N1 antibody levels among the groups related occupational exposure and AIV nucleic acid in the environment of poultry markets were detected. The characteristics of haemagglutinin (HA) genes of H5N1 AIV in the environment were analyzed.
View Article and Find Full Text PDFArticle Synopsis
- * Nine sewage samples were collected and the NS genes were amplified, sequenced, and analyzed, revealing a 90.1% - 92.6% amino acid identity with reference viruses.
- * Findings indicated that the NS1 and NS2 proteins exhibited high homology to highly pathogenic strains, suggesting a significant risk for H5N1 virus spread in these environments.
[Analysis on the hemagglutinin genetic characteristics of 2009 novel influenza A (H1N1) virus in Changsha, Hunan province].
Zhonghua Liu Xing Bing Xue Za Zhi
January 2010
Article Synopsis
- A new RT-LAMP assay was developed for quickly and accurately detecting Norwalk GII, utilizing specially designed primers targeting the RNA-dependent RNA polymerase gene.
- The assay demonstrated high specificity and sensitivity, successfully identifying 46 out of 48 fecal samples of Norwalk GII without false positives from group A rotaviruses.
- RT-LAMP was found to have similar detection limits to traditional RT-PCR but offered benefits such as faster results, making it advantageous for outbreak situations involving infectious diarrhea.
[Pathogenic diagnosis of an unexplained epidemic event of infectious diarrhea].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi
December 2008
Objective: To determine the pathogen of an unexplained epidemic event of infectious diarrhea by laboratory diagnosis of suspected cases samples.
Methods: 28 samples from 28 suspected cases (22 fecal samples, 3 vomitus samples, 3 anus swab samples) were tested for Norovirus by RT-PCR. Sequencing and phylogenetic analysis were acomplished of 5 positive samples.