Quality of life of older adult patients with heart failure with different somatic symptom profiles: The mediating role of depressive symptoms.

Aim: With an increasingly aging population, the management of heart failure (HF) in older adult patients warrants greater attention. This study aimed to identify somatic symptom profiles by using the person-oriented approach, explore the association between somatic symptom profiles and quality of life (QoL) and examine the mediating effect of depressive symptoms on this association among older adult patients with HF.

Methods: This cross-sectional study involved a convenience sample of 445 older adult patients with HF from two tertiary hospitals in China.

Trajectories and predictors of gerontological service career adaptability among health science undergraduates: A longitudinal study.

Background: In response to the aging population, it is essential to examine gerontological service career adaptability among health science undergraduates.

Objectives: This study aimed to clarify the trajectories and predictors of health science undergraduates' gerontological service career adaptability.

Design: This study adopted a longitudinal design.

Determinants of preparedness in family caregivers of patients with heart failure.

Aims: Inadequate preparedness of family caregivers contributes to adverse outcomes of patients with heart failure (HF). However, evidence on caregiver preparedness is limited. This study aims to examine the determinants and potential mechanisms of preparedness in family caregivers of patients with HF.

Association Between Benefit Finding and Self-care Management in Heart Failure Patient-Caregiver Dyads: The Mediating Role of Mutuality.

Background: Inadequate self-care management has been reported in patients with heart failure (HF) and their family caregivers. However, evidence on the influencing factors and corresponding action paths for self-care management within a dyadic context is limited.

Objective: The aim of this study was to examine dyadic associations between benefit finding and self-care management in HF patient-caregiver dyads and the mediating role of mutuality in these associations.

Efficacy of SARS-CoV-2 vaccines and the dose-response relationship with three major antibodies: a systematic review and meta-analysis of randomised controlled trials.

Background: The efficacy of SARS-CoV-2 vaccines in preventing severe COVID-19 illness and death is uncertain due to the rarity of data in individual trials. How well the antibody concentrations can predict the efficacy is also uncertain. We aimed to assess the efficacy of these vaccines in preventing SARS-CoV-2 infections of different severities and the dose-response relationship between the antibody concentrations and efficacy.