[Carotid intima media thickness and C reactive protein among overweight or obese subjects without metabolic syndrome].

Background: Recognizing cardiovascular risk in overweight adults is challenging, as they usually have a low Framingham risk score (FRAM). In these subjects, non-traditional biomarkers could improve risk stratification.

Aim: To assess carotid intima media thickness (CIMT) and ultrasensitive C-reactive protein (usCRP) among overweight and obese subjects without metabolic syndrome (MetSyn).

[Total/HDL cholesterol ratio and non HDL cholesterol as predictors for increased intima media thickness].

Background: LDL, HDL cholesterol and triglycerides, are the most commonly used lipid cardiovascular risk predictor indicators. However population based studies have shown that non-HDL cholesterol and total/HDL cholesterol ratio are better predictors, are easy to measure and do not require fasting.

Aim: To determine which lipid indicators are better determinants of subclinical atherosclerosis, measured by intima media thickness (IMT) among subjects without demonstrated atherosclerosis.

[Cardiovascular risk factors among young subjects with high carotid intima media thickness].

Background: Cardiovascular risk factor (RF) assessment is essential to prevent and predict cardiovascular disease. The presence of RF at early ages, are determinant for the presence of atherosclerosis later in life.

Aim: To determine the RF profile of young subjects with high carotid intima media thickness (CIMT).

[Resistance phenotypes and genotypes of Streptococcus pyogenes clinical isolates in Chile over a 10-year period].

Background: Macrolide and lincosamide resistance in Streptococcus pyogenes is due to the acquisition of mef, ermB and ermA genes, which confer different resistance phenotypes, namely M, MLSBconstitutive and MLSBinducible respectively. The last report of resistance in Chile was done in the period 1990-1998, in which resistance to macrolides was 5.4%, with M phenotype as the predominant one.

[Risk factors for a high carotid intima media thickness among healthy adults].

Background: Carotid intima media thickness (CIMT) is a marker of cardiovascular damage that can be modified by traditional risk factors.

Aim: To determine attributable risk factors for a high CIMT among healthy adults.

Material And Methods: A sample of 1270 individuals (636 males and 634 females) aged 44 ± 11 years, was studied.

[Early markers for atherosclerosis and metabolic syndrome in children].

Background: The high prevalence of obesity in children favors the appearance of metabolic syndrome (MS), increasing their cardiovascular risk.

Aim: To evaluate components of MS in children and to correlate them with surrogate markers of atherosclerosis and subclinical inflammation.

Material And Methods: We studied 209 children aged 11.

Adiponectin levels, cardiometabolic risk factors and markers of subclinical atherosclerosis in children.

Background: Low levels of adiponectin have been associated with metabolic risk factors (RF) and cardiac disease. Minimal data is available about the relationship between adiponectin and subclinical atherosclerosis.

Objectives: To determine the relationship of adiponectin to cardiometabolic RF, C-reactive protein (CRP), anthropometric parameters of obesity, and subclinical atherosclerosis in children.

[Relationship of C-reactive protein to adiposity, cardiovascular risk factors and subclinical atherosclerosis in healthy children].

Introduction And Objectives: In adults, C-reactive protein is a marker of cardiovascular risk. It is associated with both classical and metabolic risk factors and is a predictor of cardiovascular events. The aim was to investigate the relationship of the C-reactive protein concentration to classical cardiovascular risk factors, measures of adiposity subclinical atherosclerosis in children.

[Cost-effectiveness of health promotion in Chile. Experience with "Mirame!" program].

Background: "Mirame!" program was launched in Chile in 1993, to promote a healthy life style at school age.

Aim: To evaluate cost-effectiveness of this program.

Material And Methods: Fifth and sixth grade school children, from 5 selected municipalities of the Metropolitan Region were studied.

Post-streptococcal acute glomerulonephritis in Chile--20 years of experience.

In order to characterize the epidemiological and clinical picture of post-streptococcal acute glomerulonephritis (PSAGN), a prospective study was designed to investigate all admissions to a general hospital of a local health service in Chile. The protocol included the investigation of previous streptococcal infections (SI), clinical symptoms and signs, socioeconomic situation (SES), throat and skin swabs for the isolation of group A beta-hemolytic streptococci, sequential determination of serum antistreptolysin O (ASO) titer, anti-DNAase B antibodies, and C3. During the 20 years studied, 926 cases were admitted (56% males).