Prevalence and factors associated with carbapenem-resistant Enterobacterales (CRE) infection among hematological malignancies patients with CRE intestinal colonization.

Background: Knowledge about the prevalence, factors and mortality associated with subsequent carbapenem-resistant Enterobacterales (CRE) infection among hematological malignancies (HM) patients colonized with CRE is limited.

Methods: HM patients were screened for rectal CRE. A retrospective case-control study of subsequent CRE infection among HM patients colonized with CRE was conducted between January 1st, 2020 and January 31st, 2022.

Antibiotic Resistances and Molecular Characteristics of in ICUs in a Teaching Hospital From Central South China.

is a major healthcare-associated pathogen inducing infectious diarrhea. Approximately 25-33% of patients with antibiotic-associated diarrhea (AAD) and 90% of patients with pseudomembranous enteritis are caused by infection (CDI). Stool samples were collected from hospitalized adults with presumptive AAD in four nonneonatal intensive care units (ICUs).

Mental health status among Chinese healthcare-associated infection control professionals during the outbreak of coronavirus disease 2019: A national cross-sectional survey.

Recently, the coronavirus disease 2019 (COVID-19) epidemic has greatly threatened global public health. The responsibility of healthcare-associated infection control professionals (ICPs) is to prevent and control the nosocomial infections. The mental health status of ICPs deserves more attention, however, the correlational research is still lacking.

Assessing Molecular Epidemiology of Carbapenem-resistant Klebsiella pneumoniae (CR-KP) with MLST and MALDI-TOF in Central China.

Carbapenem-resistant K. pneumoniae (CR-KP) posts significant public health challenge worldwide. The aim of this study is to assess clinical characteristics and molecular epidemiology of CR-KP infections with Multilocus sequence typing (MLST) and Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF) in Central China.

Point prevalence survey of antimicrobial use in Chinese hospitals in 2012.

Background: In China, several measures have been adopted to decrease unnecessary antimicrobial overuse since 2010. This study aimed to identify characteristics of antimicrobial use in Chinese hospitals after implementing these measures and to explore additional targets for future antimicrobial stewardship.

Methods: In 2012, point prevalence surveys conducted in Chinese hospitals included inpatients who were admitted for at least 24 hours.

Changes in antimicrobial use prevalence in China: results from five point prevalence studies.

Objective: The abuse of antimicrobials is a serious concern in China. Several measures have been taken to improve the rational use of antimicrobials, including the establishment of a national surveillance network for antimicrobial use. This study describes the dynamic changes in antimicrobial use in China between 2001 and 2010, with the scope of identifying targets to improve the prescription of antimicrobials.

[Study on the frequency of antibiotics use per day among inpatients in 151 hospitals in 2003].

Objective: To investigate the antibiotics use in inpatients with hospitals under different scales.

Methods: On the day of August 7, 2003, antibiotics use among inpatients were investigated, medical order to each inpatient was checked and forms were filled.

Results: Data showed that 54.

[Antimicrobial resistance of Gram-negative bacilli isolated from patients in intensive care unit].

Objective: To evaluate antimicrobial resistance of Gram-negative bacilli isolated from patients in intensive care unit (ICU) and to provide guidance for clinical antimicrobial strategy.

Methods: Antimicrobial susceptibility of Gram-negative bacilli isolated from patients in ICU from 2000 to 2003 was monitored by Epsilometer test E (E-test) methods, and at the same time Whonet 5.1 was used to analyse the results.

[Incidence and pathogens of nosocomial bacteremia in China].

Objective: To investigate the incidence and pathogens of nosocomial bacteremia (NB) in China.

Methods: The data of incidence and pathogens of NB reported from Jun 1998 to Dec 2001 by the hospitals of the Chinese nosocomial infections surveillance system (CNISS) were collected and analyzed.

Results: A total of 4882364 patients were surveyed and 2 371 cases of NB were reported.