Abnormal sleep duration is associated with sarcopenia in older Chinese people: A large retrospective cross-sectional study.

Aim: Abnormalities in sleep patterns are a common health problem for the older adults. The relationship between sarcopenia and sleep duration in older people is controversial. This research is to examine the association between sleep duration and sarcopenia.

Insights in Electrochemical Determination of Quercetin in Peach Vinegar by the Hexagonal Platinum Nanocrystal.

Peach vinegar is a popular condiment that is thought to have various health benefits. However, the low levels of quercetin and complex detection environment in peach vinegar make it difficult to detect using traditional methods. Electrochemical detection is a promising solution because it is sensitive, inexpensive, and provides real-time results.

Hemodynamic Influences of Remimazolam Versus Propofol During the Induction Period of General Anesthesia: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

Background: Remimazolam is a novel ultrashort-effect benzodiazepine. In 2020, the US Food and Drug Administration approved it for procedural sedation. Remimazolam is beneficial for consistent sedation and quick recovery in painless gastrointestinal endoscopy.

Relationship between depressive symptoms and anemia among the middle-aged and elderly: a cohort study over 4-year period.

Background: The association between anemia and depression has been demonstrated in previous studies, but it's still unclear whether depressive symptoms as a hazard factor for anemia. The findings of a large-scale cross-sectional and longitudinal examination of such an association of among the middle-aged and elderly individuals in China were presented in our study.

Methods: The data from China Health and Retirement Longitudinal Study in 2011 and 2015 were evaluated.

Insights into the interaction mechanism between tiagabine hydrochloride and two serum albumins.

Tiagabine hydrochloride (TGB) is a widely used anticonvulsive drug for the treatment of epilepsy. To better understand the interactions of TGB with plasma proteins, human serum albumin (HSA) and bovine serum albumin (BSA) were selected as model proteins. TGB slightly increased thermal stability of the proteins as confirmed by VP-capillary differential scanning calorimetric (DSC) measurements.

The binding properties of metandienone and human serum albumin by comparing with other five similar compounds.

Metandienone (MET) is an exogenous anabolic androgenic steroid. The interaction between MET and human serum albumin (HSA) was investigated by molecular modeling and different optical techniques. There was no possibility of energy transfer, and the fluorescence quenching of HSA induced by MET was mainly due to the complex formation.

[Preparation and release characterization in vitro of pulsed-release tablets of compound Danshen].

Objective: To prepare pulsed-release tablet (PTS) according to the rhythm of coronary heart disease based on efficacy material and the mechanism of compound Danshen.

Method: PTS were achieved by coating the core which contains drugs, CMS-Na, lactose, succinic acid and MCC with separation layer (Eudragit RL), swelling layer (HPMC E5), and controlled-release membrane (Eudragit RS-RL-EC).

Result: The results of in vitro experiments showed that no difference was observed among the profiles of Danshensu, protocatechuic aldehyde, ginsenoside Rg1, Rb1, notoginsenoside R1 release from the two-step release system.