Publications by authors named "Xilian Wu"
Article Synopsis
- * The study analyzed gene expression data from the Cancer Genome Atlas (TCGA) to evaluate the relationship between tumor microenvironment scores and differentially expressed genes (DEGs), identifying 2346 DEGs that are linked to immune and cellular processes.
- * Ten hub genes, including ACTB and IL-6, were found to have predictive value related to patient outcomes, such as overall and disease-free survival, emphasizing their potential significance in BC prognosis.
MicroRNAs (miRNAs) play an important role in the development of prostate cancer (PCa). Recent studies have shown that miR-92a expression is significantly increased in various cancers including PCa. However, its specific mechanism in PCa remains unknown.
View Article and Find Full Text PDFBackground: Detrusor overactivity (DO) secondary to partial bladder outlet obstruction (PBOO) is closely associated with alteration of ion channels. The objective of this study is to investigate the expression of the TWIK-related arachidonic acid-activated K(+) channel (TRAAK) in the L6-S1 spinal cord of DO rats after PBOO.
Methods: Female Sprague-Dawley rats undergoing PBOO surgery were screened for DO by cystometry.
Article Synopsis
- The study aimed to investigate changes in TWIK-related arachidonic acid-activated K(+) channels in the spinal cord of rats after bladder obstruction and its effects on bladder dysfunction.
- Female Sprague-Dawley rats underwent either complete bladder outlet obstruction or a sham procedure, with subsequent analysis of spinal cord tissue for channel expression using various techniques.
- Findings indicated lower expression of these channels in obstructed rats, suggesting that their downregulation may contribute to increased neuronal activity and heightened bladder sensitivity, offering insights into overactive bladder conditions resulting from such obstructions.