Sandwiching Phosphorene with Iron Porphyrin Monolayer for High Stability and Its Biomimetic Sensor to Sensitively Detect Living Cell Released NO.

Instability of 2D phosphorene material is the major obstacle for its broad applications. Herein phosphorene is sandwiched with self-assembled iron porphyrin monolayers on both sides (I-Phene) to significantly enhance stability. Iron porphyrin has strong interaction with phosphorene through formation of PFe bonds.

Molecularly assembled graphdiyne with atomic sites for ultrafast and real-time detection of nitric oxide in cell assays.

Nitric oxide as a signal molecule participates in a variety of physiological and pathological processes but its real-time detection in cell assays still faces challenging because of the trace amount, short half-life and easy conversion to other substances. We report here a rational design by assembling highly π-conjugated and small capacitive gaphdiyne (GDY) with a coordination complex of hemin (HEM) into a molecularly assembled material of GDY/HEM to achieve ultrafast and real-time monitoring of nitric oxide in cell assays. GDY comprising alkynyl C atoms can hybridize with the HEM to enable strong π-π interaction and atomic dispersion of iron sites while avoiding the formation of catalytically inactive dimer for the HEM.

[Mechanism of weightlessness osteoporosis and preventive and therapeutic effect of traditional Chinese medicine].

Weightlessness environment can lead to the muscle atrophy and body fluid distribution upward,which can cause the bone calcium metabolism disorder and always accompanied by the loss of bone microstructure and increased rate of bone fracture. Under microgravity,the astronauts are much easier to decrease the Ca2+ ion in bone, which can cause serious osteoporosis. However the bone lost is not equilibrium, it is especially serious in the mechanism loading bone and the recovery process is more difficult.