Synopsis of recent research by authors named "Xijie Dong"
- Xijie Dong's recent research primarily focuses on the immune system's alterations in septic shock and sepsis, particularly the role and dysfunction of B cells during these critical conditions, highlighting their contribution to immunosuppression and poor patient prognoses.
- Key findings from his studies indicate that mechanisms such as intrinsic/extrinsic apoptosis and pyroptosis are implicated in the selective depletion of B cell subsets, which correlates with the severity and mortality of septic patients.
- Dong's work also explores the relationship between immune cell alterations in severe trauma patients and their subsequent risk of developing sepsis, providing insights into how early immune changes can predict patient outcomes.
