Publications by authors named "Xihuan Zou"
Background: Radon, a potent carcinogen, is a significant catalyst for lung cancer development. However, the molecular mechanisms triggering radon-induced lung cancer remain elusive.
Methods: Utilizing a radon exposure concentration of 20,000 Bq/m3 for 20 min/session, malignant transformation was induced in human bronchial epithelial cells (BEAS-2B).
Article Synopsis
- * The study hypothesized that lactate dehydrogenase (LDH), specifically its subunits LDHA and LDHB, plays a role in the Warburg effect in cells transformed by the carcinogen MNNG.
- * Results showed that exposure to MNNG increased cell proliferation and lactate production; knocking down LDHA or LDHB reduced these effects, while overexpressing them promoted malignant transformation, enhancing the Warburg effect.
The purpose of this meta-analysis was to evaluate the relationship between serum 25-hydroxyvitamin D[25(OH)D] levels and gastric cancer. PubMed, Embase, Cochrane Library, Web of Science, The China Academic Journals full-text database, Wanfang Database of Chinese Academic Journals, VIP Chinese Science and Technology Periodicals database, and Chinese Biomedical Literature database were systematically searched. Case-control studies on the correlation between serum 25-hydroxyvitamin D levels and gastric cancer were retrieved, and the data extracted were analyzed.
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