Publications by authors named "Xiening Wu"

Objective: To investigate the anti-inflammatory effect and mechanisms of interleukin-35 (IL-35) in inflammatory bowel disease.

Methods: BALB/c mice were divided into three groups with 10 mice in each group:control group, model group (oral administration of 4% glucan sodium sulfate for 7 d) and IL-35-treated group (oral administration of 4% glucan sodium sulfate for 7 d, intraperitoneal injection of 2 μg IL-35 at d2-5). Disease activity index (DAI) was scored every day.

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Article Synopsis
  • - Multiple endocrine neoplasia type 1 (MEN1) is a rare genetic syndrome that increases the risk of tumors in endocrine glands like the parathyroids, pituitary, pancreas, and gastrointestinal tract.
  • - A patient with a history of pituitary adenoma experienced chronic diarrhea, gastrointestinal bleeding, and perforation, with imaging revealing pancreatic and duodenal nodules and enlarged parathyroid glands.
  • - After surgical interventions including partial parathyroidectomy and pancreaticoduodenectomy, the patient recovered well, suggesting that symptoms like intestinal perforation and bleeding may indicate Zollinger-Ellison Syndrome in MEN1 patients.
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Guidelines for treatment of severe acute pancreatitis.

Hepatobiliary Pancreat Dis Int

August 2002

Severe acute pancreatitis is a disease of rapid onset and progression with high mortality and morbidity. A new concept suggests that it is multifactorially induced and involves multi-links and that therapy must be directed to several more important links at the same time. The regimen of integrated traditional Chinese and western medicine acts on the same or different sites and links to inhibit or block the inflammatory cascades.

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