Portable sensing of hydrogen peroxide using MOF-based nanozymes.

Hydrogen peroxide (HO) is extensively used in water treatment and food preservation for its pathogen-killing efficacy. Excessive HO intake, however, can lead to poisoning with symptoms such as abdominal pain and breathing difficulties. Additionally, small amounts of HO may be generated during food preservation, necessitating careful control to meet safety regulations.

Polyphenol compounds contributing to the improved bioactivities of fermented Rubus chingii Hu.

This research aims to evaluate the phenolic composition, antioxidant and enzyme inhibition activities of fermented Rubus chingii Hu wine, and explore the correlation between them. TPC (Total Phenolic content) and TFC (Total Flavonoid content) increased rapidly from 0 h to 72 h, followed by a slight decrease in TPC and a significant decrease in TFC. Fermentation could significantly increase the antioxidant activity and α-amylase/α-glucosidase enzyme inhibitory activity of Rubus chingii Hu.

Texture, swallowing and digestibility characteristics of a low-GI dysphagia food as affected by addition of dietary fiber and anthocyanins.

Dysphagia is a common problem in the elderly population, thus texture modifications in foods suitable for dysphagic patients aroused a lot of interest. In the study, low glycemic index (GI) dysphagia foods were designed with adding dietary fiber (DF) and anthocyanins (AS), and their in vitro enzymatic digestion and predicted GI values were investigated by first-order kinetic model and slope log model. Results showed that all samples belonged to dysphagia foods at level 4 (pureed) in the International Dysphagia Diet Standardization Initiative (IDDSI) framework, and exhibited shear thinning behavior.

Ultra-fast photoelectron transfer in bimetallic porphyrin optoelectrode for single neuron modulation.

Shrinking the size of photoelectrodes into the nanoscale will enable the precise modulation of cellular and subcellular behaviors of a single neuron and neural circuits. However, compared to photovoltaic devices, the reduced size causes the compromised efficiencies. Here, we present a highly efficient nanoelectrode based on bimetallic zinc and gold porphyrin (ZnAuPN).

A novel triple signal amplification platform of peroxide test strip for sensitive detection of adenosine triphosphate.

Peroxide test strip (PTS) has been widely used for the point-of-care testing (POCT), but its poor sensitivity is a big obstacle for analyzing trace target. Herein, a triple signal amplifying platform integrating the liposome enrichment, the hybridization chain reaction (HCR) circuit, and the image analysis method was constructed to enhance the visual readout of PTS for the sensitive detection of adenosine triphosphate (ATP), an important biomarker of food spoilage. In the presence of ATP, the HCR amplifier was firstly initiated on the surface of magnetic beads (MBs), inducing a large number of glucose oxidase (GOD) imbedded liposomes to be attached.

Chinese Populations of Serving as a Source of Human-Mediated Gene Flow to Asian Countries: A Population Genomic Analysis.

, a filamentous heterothallic ascomycete fungus that serves as the causative agent of rice blast disease, is globally distributed in rice-growing regions. Populations shaped by environmental factors and human intervention play important roles in the formation of genetic structure. In this study, population structures and spatiotemporal dynamics were investigated based on large-scale whole genomic sequences of rice-infecting around the world.

Dual (oxy)hydroxide Cocatalyst Synergistically Boosts Solar Water Splitting of BiVO Photoanode.

Bismuth oxide (BiVO) is considered one of the most promising semiconductors for photoelectrochemical (PEC) water splitting due to its highly theoretical photocurrent of 7.5 mA cm. However, its sluggish kinetics and severe photocorrosion still hinder the real application of a large-area BiVO photoanode.

Major sight-threatening eye disorders and mental disorders.

The purpose of this study was to: (a) investigate the comorbidities of major sight-threatening eye disorders with mental disorders, (b) investigate the associations and prevalence of reported comorbidities and (c) identify potential influencing factors. A systematic review of the PubMed, Embase, Web of Science and Cochrane Library databases was conducted from inception to 30 December 2023. Studies that presented only laboratory results or used non-representative sampling methods were excluded.

Sustainable Lithography Paradigm Enabled by Mechanically Peelable Resists.

Lithography is critical in micro- and nanofabrication processes, enabling the development of integrated circuits, semiconductor devices, and various advanced electronic and photonic systems. However, there are challenges related to sustainability, efficiency, and yield, as well as compatibility with transient electronics. This work introduces a sustainable lithography paradigm employing mechanically peelable resists compatible with existing cleanroom processes.

Organotropic Engineering of Luminescent Gold Nanoclusters for In Vivo Imaging of Lung Orthotopic Tumors.

Gold nanoclusters (AuNCs) are emerging as promising functional probes for bioapplications. However, because of rapid renal clearance, it is a challenge to tailor their biofate and improve their disease-targeting ability in vivo. Herein, we report an efficient strategy to tailor their organotropic actions by rationally designing AuNC assemblies.

Functional Monitoring of Patients With Knee Osteoarthritis Based on Multidimensional Wearable Plantar Pressure Features: Cross-Sectional Study.

Background: Patients with knee osteoarthritis (KOA) often present lower extremity motor dysfunction. However, traditional radiography is a static assessment and cannot achieve long-term dynamic functional monitoring. Plantar pressure signals have demonstrated potential applications in the diagnosis and rehabilitation monitoring of KOA.

Epoxidized Single-Atom Co-N-C Catalysts Promote the Oxygen Reduction Reaction via a Two-Electron Pathway.

Coordination structure and group modifications of single-atom catalysts are essential for regulating superficial electronic structures and reaction activities. Epoxy group-modified single-atom Co-N-C configuration demonstrates exceptional catalytic performance for hydrogen peroxide production. Through the manipulation of the coordination structure of Co-N-C and the doped epoxy groups, we elucidate the origin of catalytic activity in epoxygroup-modified Co-N-C configurations.

Orientation-modulated oxygen evolution reaction in epitaxial SrRuO films.

The SrRuO films were grown on SrTiO using a lattice matching strategy. Scanning electrochemical microscopy imaged local oxygen evolution reaction (OER) performance, exploring the relationship between micro-area activity and the termination layer. Combined with traditional electrochemical methods and DFT calculations, the OER activity was correlated with the electronic structure.

Effects of different slaughtering methods on the biochemical characteristics and quality changes of tilapia () during cold storage.

Inappropriate slaughter methods can lead to differences in fish quality. In the past few years, few studies have focused on the effects of different slaughter methods on the postmortem effects of tilapia, especially the cold storage of tilapia after slaughter. The aim of this study was to investigate the effects of different slaughter methods on the biochemical characteristics and quality changes of tilapia during cold storage.

Dentin tubules as a long-term sustained release carrier to accelerate bone repair by loading FTY720.

The controlled release of drugs remains a huge challenge in the field of tissue engineering. Current research focuses on the construction of drug carriers by using various advanced technologies. However, the pore-like structure that exists within our human body is ignored.

Ages-specific beverage consumption and its association with depression and anxiety disorders: A prospective cohort study in 188,355 participants.

Background: Diet habit is associated with mental health which has been suggested to be an independent risk factor. Nevertheless, evidence concerning the association between beverage consumption and age-specific mental health remains limited. Here we estimate the association between six types of beverages and depression and anxiety disorders.

Enhancing indoor air quality and cardiopulmonary health in patients with asthma by photocatalytic oxidation and filters air cleaner.

Background: Air purifiers can enhance indoor air quality and health outcomes, and studies have primarily focused on filters and particulate matter (PM) in households. Photocatalytic oxidation (PCO) is a promising technique for eliminating gaseous pollutants and bioaerosols. However, no field study was conducted in household.

Qibai Pingfei Capsule ameliorated inflammation in chronic obstructive pulmonary disease (COPD) via HIF-1 α/glycolysis pathway mediated of BMAL1.

Background: Chronic obstructive pulmonary disease (COPD) is characterized for the persistent inflammation. The brain and muscle arnt-like 1 (BMAL1), as a crucial clock gene, is associated with the expression level of upstream factor hypoxia-inducible factor (HIF)-1α in glycolysis, which may affect the occurrence of inflammatory reactions in COPD. However, the moderation effect of Qibai Pingfei Capsule (QBPF) capsule is still unknown on BMAL1 and HIF-1α/glycolytic pathway.