Based on sodium alginate coatings and dendritic copolymeric modification of curcumin delivery system: pH-sensitive nanospheres and strong tumor cytotoxicity.

This study aims to construct a novel drug delivery strategy to address the poor bioavailability and biostability of curcumin. A curcumin delivery strategy, basing on post-polymerization modification of poly(2-vinyl-4,4-dimethyl azlactone) to obtain conjugates of curcumin and dendritic polymers, combined with sodium alginate coating is reported. The curcumin-polymer conjugates were shown to have good fluorescence properties with fluorescence quantum yields of 0.

Strategies based on -carborane embedded indole fluorescent polymers: their synthesis, spectral properties and cell imaging studies.

The continuous preparation scheme EPO-Poly-indol--carborane (E-P-INDOLCAB), L100-55-Poly-indol--carborane (L-P-INDOLCAB), RS-Poly-indol--carborane (S-P-INDOLCAB), and RL-Poly-indol--carborane (R-P-INDOLCAB) were used to prepare the four types of acrylic resin-coated nido-carborane indole fluorescent polymers. After testing their spectral properties and the fluorescence stability curve trend at various acidic pH values (3.4 and 5.

Design, synthesis, and antitumor activity evaluation of BF-o, m, p-phenylenediamine bridged with pyrimidine-indole BF adduction derivatives.

Fluorescent drugs and pyrimidine-indole scaffolds have been shown to have advantages in cancer treatment. Fluorescent antitumor drugs BF-o, m, p-phenylenediamine pyrimidine-indole derivatives (PYB1, PYB2, and PYB3) were synthesized by linking pyrimidine and indole groups with aniline through a simple step and introducing BF. The drugs exhibit promising antitumor activity and their fluorescent properties make them useful for imaging purposes.