Degradation and detoxification of aflatoxin B1 by two peroxidase enzymes from Irpex lacteus F17.

Aflatoxin B1 (AFB1), the most toxic mycotoxin produced by some Aspergillus species, is commonly found in agricultural products, especially grains, and poultry feeds. Enzymic degradation is considered to be the most promising detoxification method, because it is efficient, safe and causes minimal damage to the nutritional quality of treated foods. In this study, a recombinant manganese peroxidase (Il-MnP1) and a recombinant dye-decolorizing peroxidase (Il-DyP4) from Irpex lacteus F17 were used to degrade AFB1, either individually or in combination.

MiR-222-3p in Platelets Serves as a Distinguishing Marker for Early Recognition of Kawasaki Disease.

Kawasaki disease (KD) is an acute vasculitis, which leads to 20% of sufferers developing coronary artery aneurysm in children if not appropriately treated. Therefore, the early diagnosis of KD is essential for alleviating the risk of developing heart disease. MicroRNAs (miRNAs) are a large class of small non-coding RNAs which post-transcriptionally regulate gene expression and have been shown to play critical roles in numerous biological processes and diseases.