Publications by authors named "Xiaozheng Fan"

Background: The primary limitation to kidney transplantation is organ shortage. Recent progress in gene editing and immunosuppressive regimens has made xenotransplantation with porcine organs a possibility. However, evidence in pig-to-human xenotransplantation remains scarce, and antibody-mediated rejection (AMR) is a major obstacle to clinical applications of xenotransplantation.

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Article Synopsis
  • Upper tract urothelial carcinoma (UTUC) is a rare cancer with poor prognosis, and this study explores the effects of adjuvant treatment using tislelizumab, with or without chemotherapy, on patients after surgery.
  • A retrospective analysis of 63 high-risk UTUC patients showed that most responded positively, with 78% achieving stable disease after treatment, and the two-year survival rates were favorable.
  • However, 92% of patients experienced some treatment-related side effects, indicating the treatment's manageable safety profile despite the presence of serious adverse reactions in some cases.
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Renal cell carcinoma (RCC) is the most common malignant tumor in the urinary system, accounting for 80 % to 90 % for all renal malignancies. Traditional diagnostic methods like magnetic resonance imaging (MRI) and computed tomography (CT) lack the sensitivity and specificity as they lack specific biomarkers. These limitations impede effective monitoring of tumor recurrence.

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Renal cell carcinoma is one common type of urologic cancers. It has tendencies to invade into the inferior vena cava (IVC) and usually requires an open surgery procedure. High rates of operative complications and mortality are usually associated with an open surgery procedure.

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Pleckstrin homology-like domain family A, member 3 (PHLDA3) is a novel tumor-related protein that mediates carcinogenesis of multiple cancers. However, the relevance of PHLDA3 in prostate cancer has not been explored. The purpose of this work was to illustrate the possible roles and mechanisms of PHLDA3 in prostate cancer.

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In this paper, the fuzzy [Formula: see text] output-feedback control problem is investigated for a class of discrete-time T-S fuzzy systems with channel fadings, sector nonlinearities, randomly occurring interval delays (ROIDs) and randomly occurring nonlinearities (RONs). A series of variables of the randomly occurring phenomena obeying the Bernoulli distribution is used to govern ROIDs and RONs. Meanwhile, the measurement outputs are subject to the sector nonlinearities ( the sensor saturations) and we assume the system output is [Formula: see text], [Formula: see text].

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