Synopsis of recent research by authors named "Xiaoyun Yun"
- Xiaoyun Yun's recent research focuses on the mechanisms and treatments related to autoimmune diseases, particularly rheumatoid arthritis (RA), exploring the roles of p53 mutations, age-related DNA accumulation, and potential therapeutic agents such as epalrestat and natural compounds like tricin and licochalcone B.
- His studies also delve into the molecular pathways of RA pathogenesis, such as the TBK1-IRF3 innate immune response and the impact of non-coding RNAs on disease management, highlighting the intricate relationships between inflammation and immune system dysfunction.
- Additionally, Yun's research includes efforts to repurpose existing medications for novel applications, as seen in his investigation of antimalarial drugs targeting the papain-like protease of SARS-CoV-2, reflecting a broader interest in translational medicine and therapeutic innovation.