A network pharmacology approach to explore and validate the potential targets of ginsenoside on osteoporosis.

Osteoporosis (OP) is determined as a chronic systemic bone disorder to increase the susceptibility to fracture. Ginsenosides have been found the anti-osteoporotic activity of in vivo and in vitro. However, its mechanism remains unknown.

The nonlinear association between albumin levels and risk of noninvasive fungal rhinosinusitis.

Purpose: The preoperative diagnosis of noninvasive fungal rhinosinusitis (NIFRS) is inaccurate, and biomarkers to assist the diagnosis are urgently needed. We aimed to evaluate the relationship between albumin levels and NIFRS to assist in early diagnosis.

Methods: Patients with NIFRS and chronic sinusitis were enrolled in this study.

Development and Validation of a Prognostic Model to Predict Hearing Recovery for Patients With Chronic Otitis Media.

Objective: To explore the factors affecting postoperative hearing recovery in chronic otitis media (COM) patients, establish a clinical prediction model for hearing recovery, and verify the accuracy of the model.

Methods: Data of patients with COM who were admitted to our hospital between January 1, 2012 and September 30, 2020 were retrospectively analyzed. We collected data on relevant clinicopathological characteristics of patients.

Analysis of Genetic Alteration Signatures and Prognostic Values of m6A Regulatory Genes in Head and Neck Squamous Cell Carcinoma.

Genetic alteration involving N6-methyladenosine (m6A) regulatory genes is a frequent characteristic of multiple tumors. Nevertheless, little is known regarding their genetic alteration signatures and prognostic values in head and neck squamous cell carcinoma (HNSCC). In this study, RNA sequence profiles and copy number variation (CNV) data of 506 HNSCC patients were downloaded from The Cancer Genome Atlas (TCGA) database.

Coblation tonsillectomy versus coblation tonsillectomy with ties in adults.

Objective: This study was performed to compare the intraoperative and postoperative courses of coblation tonsillectomy and coblation tonsillectomy with ties in adults.

Methods: All patients who underwent tonsillectomy from July 2012 to September 2016 were retrospectively reviewed. Intraoperative and postoperative bleeding, pain, and return to normal food intake were compared between patients who underwent coblation tonsillectomy and those who underwent coblation tonsillectomy with ties.

Physiological Ischemic Training Promotes Brain Collateral Formation and Improves Functions in Patients with Acute Cerebral Infarction.

Objectives: To observe the effectiveness and mechanisms of physiological ischemic training (PIT) on brain cerebral collateral formation and functional recovery in patients with acute cerebral infarction.

Methods: 20 eligible patients with acute cerebral infarction were randomly assigned to either PIT group ( = 10) or Control group ( = 10). Both groups received 4 weeks of routine rehabilitation therapy, while an additional session of PIT, which consisted of 10 times of maximal voluntary isometric handgrip for 1 min followed by 1 min rest, was prescribed for patients in the PIT groups.

[Vapor extraction technology in oil contaminated soil remediation].

In order to study the Vapor Extraction Technology that can be applied to China, on the basis of mechanism analysis of Vapor Extraction Technology for oil-contaminated soil, a simplified and practical contaminant removal model to simulate the soil remediation time was presented. With the typical unsaturated soils in North of China, the effects of the vapor flow rate, soil water content and quality on the remediation process were studied. The results showed that the best value of flow velocity was existed, and water content had different influence on different kinds of soil, for silty soil, the efficiency of remediation enhanced with water content increase, but there was a reverse result for clayey soil.