Nanobody-Induced Aggregation of Gold Nanoparticles: A Mix-and-Read Strategy for the Rapid Detection of .

Protein-nanoparticle interactions play a crucial role in both biomedical applications and the biosafety assessment of nanomaterials. Here, we found that nanobodies can induce citrate-capped gold nanoparticles (AuNPs) to aggregate into large clusters. Subsequently, we explored the mechanism behind this aggregation and proposed the "gold nucleation mechanism" to explain this phenomenon.

Advances of biomacromolecule-based antibacterial hydrogels and their performance evaluation for wound healing: A review.

Biomacromolecule hydrogels possess excellent mechanical properties and biocompatibility, but their inability to combat bacteria restricts their application in the biomedical field. With the increasing requirements and demands for hydrogel dressings, wound dressings with antibacterial properties of biomacromolecule hydrogels reinforced by adding antibacterial agents have attracted much attention, and related reviews are emerging. In this paper, the advances of biomacromolecule antibacterial hydrogels (including chitosan, sodium alginate, Hyaluronic acid, cellulose and gelatin) were first overviewed, and the antibacterial agents incorporated into hydrogels were classified (including metals and their derivatives, carbon-based materials, and native compounds).

Europium functionalized porphyrin-based metal-organic framework heterostructure and hydrogel for visual ratiometric fluorescence sensing of sulfonamides in foods.

Protecting human health and ensuring food security require the swift and accurate detection of sulfonamides (SAs) residues in foods. Herein, we proposed an Eu-postfunctionalized bimetallic porphyrin metal-organic framework (PCN-221(Zr/Ce)@Eu-DPA-Hbtec) synthesized solvothermally for fluorescence sensing. The PCN-221(Zr/Ce)@Eu-DPA-Hbtec fluorescent sensor demonstrated excellent stability and high selectivity to SAs, and the detection limits of sulfamethazine (SM), sulfamerazine (SMR), and sulfamethoxydiazine (SMD) were as low as 56 nmol/L, 45 nmol/L, and 56 nmol/L, respectively.

Mechanism insight into the high-efficiency catalytic killing of by metal-phenolic network as a nanozyme.

Glutathione (GSH) as an antioxidant greatly attenuates the reactive oxygen species (ROS) treatment strategy based on peroxidase-activity nanozymes. Therefore, nanozymes with multiple properties that generate ROS and further GSH-depletion functions would be of great benefit to improve antimicrobial efficacy. Herein, focusing on the green, safe and abundant functional prospects of metal-phenolic networks (MPNs) and the strong prospect of biomedical applications, we have synthesized copper tannic acid (CuTA) nanozymes with dual functional properties similar to peroxidase-like activity and GSH depletion.

Rapid Trace Detection of Sulfite Residue in White Wine Using a Multichannel Colorimetric Nanozyme Sensor.

As a commonly used food additive, sulfite (SO) is popular with food manufacturers due to the functions of bleaching, sterilizing, and oxidation resistance. However, excess sulfites can pose a threat to human health. Therefore, it is particularly important to achieve rapid and sensitive detection of SO.

Fluorescent and smartphone imaging detection of tetracycline residues based on luminescent europium ion-functionalized the regular octahedral UiO-66-NH.

Antibiotic residues cause extensive damage to food security, thus arousing serious concerns. Hence, rapid and sensitive detection of antibiotic residues is crucial to food safety. This study aimed to propose a portable, visual, intelligent and rapid method for tetracycline detection.

Lanthanide bimetallic MOF-based fluorescent sensor for sensitive and visual detection of sulfamerazine and malachite.

A lanthanide terbium/europium metal-organic framework (TbEu-MOF) was prepared by one-step solvothermal method at room temperature. A series of characterizations including scanning electron microscopy, powder X-ray diffraction spectra, Fourier transform infrared spectra and X-ray photoelectron spectroscopy were carried out to clarify the physical characteristics of the synthesized material. The data clarified that the prepared TbEu-MOF possessed rod-like morphology with a width of 1-2 μm, and had good crystal structure, good stability, response speed and excitation-independent emission feature.

Fluorescent Sensing of Ciprofloxacin and Chloramphenicol in Milk Samples via Inner Filter Effect and Photoinduced Electron Transfer Based on Nanosized Rod-Shaped Eu-MOF.

Rapid, facile, and accurate detection of antibiotic residues is vital for practical applications. Herein, we designed a sensitive, visual, and rapid analytical method for sensitive detection of ciprofloxacin and chloramphenicol based on a nanosized rod-shaped Europium metal organic framework (Eu-MOF). The fluorescent Eu-MOF was firstly synthesized by a simple synthetic route at room temperature, which displays a red emission.

Three-dimensional porous carbon derived from different organic acid salts for application in electrochemical sensing.

Three-dimensional porous carbon materials were synthesized by the one-step pyrolysis of organic salts with different numbers of hydroxyl groups on the side chain (sodium tartrate, sodium malate and sodium succinate). Further, the formation of these porous carbon materials was explored. And then, three kinds of carbon materials were used for constructing electrochemical sensors for nitrite detection, respectively.

A facile fluorescent sensor based on nitrogen-doped carbon dots derived from for highly selective and visual detection of iodide and pH.

Sensitive and visual analysis of iodide (I) and pH is significant in environmental and food applications. Herein, we present a facile fluorescent sensor for highly selective and visual detection of I and pH based on nitrogen-doped carbon dots derived from (NCDs-LM). The NCDs-LM-based fluorescent sensor showed a good linear relationship to I concentrations, and the detection limit was calculated as 20 nmol L.

A portable smartphone-assisted ratiometric fluorescence sensor for intelligent and visual detection of malachite green.

Developing intelligent, sensitive, and visual methods for rapidly detecting veterinary drug residues is essential for ensuring food quality and safety. A portable smartphone-assisted ratiometric fluorescent sensor was successfully designed using fluorescent Al-MOF nanosheet and rhodamine B (RhB) as fluorescent probes to adjust to the requirement of malachite green (MG) detection. The developed ratiometric fluorescent sensor allowed sensitive and selective detection of MG with good linear relationships in a wide range of 0.

Inner-filter effect induced fluorescent sensor based on fusiform Al-MOF nanosheets for sensitive and visual detection of nitrofuran in milk.

Developing highly sensitive and visual methods for rapid detection of antibiotics is significant to ensure food quality and safety. To meet the requirement of nitrofuran antibiotics detection, luminescent fusiform Al(III)-containing metal-organic frameworks (Al-MOF) nanosheets were successfully synthesized by one-step hydrothermal method. And then, the nanosheet served as a fluorescent probe to detect nitrofuran via the inner-filter effect mechanism.

Peptide-conjugated hemin/G-quadruplex as a versatile probe for "signal-on" electrochemical peptide biosensor.

In this work, a novel "signal-on" electrochemical peptide biosensor based on peptide-conjugated hemin/G-quadruplex (DNAzyme-peptide) hybrid and rosebud-like MoSe@reduced graphene oxide (MoSe@rGO) nanocomposite, was developed for detection of prostate-specific antigen (PSA). Interestingly, the peptide not only served as recognition probe to detect PSA, but also acted as the enhancer to improve the enzyme activity of hemin/G4, which promoted the detection sensitivity. Up addition of PSA, FeO-labeled DNAzyme-peptide probe was cleaved, followed by the magnetic separation.

Selective electrochemical determination of tertiary butylhydroquinone in edible oils based on an in-situ assembly molecularly imprinted polymer sensor.

Developing selective and sensitive methods for tertiary butylhydroquinone (TBHQ) detection is of great significance to ensure the quality and safety of food. Herein, an electrochemical sensor was designed for selective and sensitive detection of TBHQ by integrating molecularly imprinted polymer, noble metal nanoparticles and carbon materials. The electrochemical sensor exhibited excellent performance for sensitive determination of TBHQ.

Highly specific and sensitive determination of propyl gallate in food by a novel fluorescence sensor.

Propyl gallate (PG), one of the most widely used synthetic phenolic antioxidants in edible oil, cookies and fried food, has received extensive concern due to its possible toxic effects on human health. Herein, a novel fluorescence analytical method is firstly proposed to sensitively and selectively determine propyl gallate (PG) by utilizing the unique fluorescence quenching property of organic molybdate complex (OMC) formed by the specific reaction between MoO and PG to g-CN nanosheets. Under the optimum conditions, the developed fluorescence sensor allows highly sensitive detection of PG in a wide range from 0.

Au Promoted Nickel-Iron Layered Double Hydroxide Nanoarrays: A Modular Catalyst Enabling High-Performance Oxygen Evolution.

Oxygen evolution reaction (OER) plays a key role in various energy conversion and storage technologies, such as water electrolysis, regenerative fuel cells, and rechargeable metal-air batteries. However, the slow kinetics of OER limit the performance and commercialization of such devices. Herein, we report on NiFe LDH@Au hybrid nanoarrays on Ni foam for much enhanced OER.

Highly Sensitive and Selective Determination of Tertiary Butylhydroquinone in Edible Oils by Competitive Reaction Induced "On-Off-On" Fluorescent Switch.

As one of most common synthetic phenolic antioxidants, tertiary butylhydroquinone (TBHQ) has received increasing attention due to the potential risk for liver damage and carcinogenesis. Herein, a simple and rapid fluorescent switchable methodology was developed for highly selective and sensitive determination of TBHQ by utilizing the competitive interaction between the photoinduced electron transfer (PET) effect of carbon dots (CDs)/Fe(III) ions and the complexation reaction of TBHQ/Fe(III) ions. This novel fluorescent switchable sensing platform allows determining TBHQ in a wider range from 0.

Nickel sulfide microsphere film on Ni foam as an efficient bifunctional electrocatalyst for overall water splitting.

Developing low-cost, efficient, and bifunctional electrocatalysts for both the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is an appealing yet challenging task. Herein, for the first time, a NiS microsphere film was grown in situ on Ni foam (NiS/Ni foam) via a sulfurization reaction as an efficient bifunctional electrocatalyst for overall water splitting with superior activity and good durability. This NiS/Ni foam electrode delivers 20 mA cm(-2) at an overpotential of 158 mV for the HER and 50 mA cm(-2) at an overpotential of 335 mV for the OER in 1.

DNA-mediated gold nanoparticle signal transducers for combinatorial logic operations and heavy metal ions sensing.

Herein, the structure of two DNA strands which are complementary except fourteen T-T and C-C mismatches was programmed for the design of the combinatorial logic operation by utilizing the different protective capacities of single chain DNA, part-hybridized DNA and completed-hybridized DNA on unmodified gold nanoparticles. In the presence of either Hg(2+) or Ag(+), the T-Hg(2+)-T or C-Ag(+)-C coordination chemistry could lead to the formation of part-hybridized DNA which keeps gold nanoparticles from clumping after the addition of 40 μL 0.2M NaClO4 solution, but the protection would be screened by 120 μL 0.